Early Intensive Intervention for Children with Autism Spectrum Disorder: A Systematic Review Update

Project Summary Title and Description

Title
Early Intensive Intervention for Children with Autism Spectrum Disorder: A Systematic Review Update
Description
The objective of this study was to systematically review studies of early intensive behavioral and developmental approaches that may improve outcomes for children with ASD.
Attribution
N/A
Authors of Report
N/A
Methodology description
Our primary literature search employed three databases: MEDLINE® via the PubMed interface, PsycINFO® (psychology and psychiatry literature), and the Educational Resources Information Clearinghouse. Our search strategies used a combination of subject heading terms appropriate for each database and key words relevant to ASD (e.g., autism, Asperger). We limited searches to the English language and literature published since the development of the 2011 AHRQ review on management of ASD. Two reviewers independently assessed studies against predetermined inclusion/exclusion criteria. Two reviewers independently extracted data regarding participant and intervention characteristics, assessment techniques, and outcomes and assigned quality and strength of evidence ratings using predetermined methods.
PROSPERO
N/A
DOI
10.26300/40xv-7134
Notes
http://effectivehealthcare.ahrq.gov/search-for-guides-reviews-and-reports/?pageaction=displayproduct&productid=1945 PMID: 25210724 Data was entered retrospectively. "ASD update data for SRDR_final to upload.xlsx" file contains outcome data for this project.
Funding Source
This project was supported by the Agency for Healthcare Research and Quality (contract number: HHSA290201200009I)

Key Questions

1. ASD Update Data KQ1: Among children ages 2-12 with ASD, what are the short and long-term effects of available behavioral treatment approaches? Specifically, KQ1a: What are the effects on core symptoms (e.g., social communication and interaction, restricted and repetitive behaviors), in the short term (≤6 months)? KQ1b: What are the effects on commonly associated symptoms (e.g., motor, medical, mood/anxiety, irritability, and hyperactivity) in the short term (≤6 months)? KQ1c: What are the longer-term effects (>6 months) on core symptoms (e.g., social communication and interaction, restricted and repetitive behaviors)? KQ1d: What are the longer-term effects (>6 months) on commonly associated symptoms (e.g., motor, medical, mood/anxiety, irritability, and hyperactivity)? KQ2: Among children ages 2-12, what are the modifiers of outcome for different behavioral treatments or approaches? KQ2a: Is the effectiveness of the therapies reviewed affected by the frequency, duration, and intensity of the intervention? KQ2b: Is the effectiveness of the therapies reviewed affected by the training and/or experience of the individual providing the therapy? KQ2c: What characteristics, if any, of the child modify the effectiveness of the therapies reviewed? KQ2d: What characteristics, if any, of the family modify the effectiveness of the therapies reviewed? KQ3: Are there any identifiable changes early in the treatment phase that predict treatment outcomes? KQ4: What is the evidence that effects measured at the end of the treatment phase predict long-term functional outcomes? KQ5: What is the evidence that specific intervention effects measured in the treatment context generalize to other contexts (e.g., people, places, materials)? KQ6: What evidence supports specific components of behavioral treatment as driving outcomes, either within a single treatment or across treatments? KQ7: What evidence supports the use of a specific behavioral treatment approach in children under the age of two 2 who are at high risk of developing autism ASD based upon behavioral, medical, or genetic risk factors?

Associated Extraction Forms

Associated Studies (each link opens a new tab)

TitleAuthorsYear
Comparative efficacy of LEAP, TEACCH and non-model-specific special education programs for preschoolers with autism spectrum disorders2013
Measuring and Supporting Language Function for Children with Autism: Evidence from a Randomized Control Trial of a Social-Interaction-Based Therapy2013
Longitudinal follow-up of children with autism receiving targeted interventions on joint attention and play.2012
Group cognitive behavior therapy for children with high-functioning autism spectrum disorders and anxiety: a randomized trial.
Parent inclusion in Early Intensive Behavioral Intervention: the influence of parental stress, parent treatment fidelity and parent-mediated generalization of behavior targets on child outcomes.-- Not Found --
Making the connection: randomized controlled trial of social skills at school for children with autism spectrum disorders.
A pilot randomized controlled trial of DIR/Floortime™ parent training intervention for pre-school children with autistic spectrum disorders.2011
Effects of cognitive-behavioral therapy on anxiety in children with autism spectrum disorders: a randomized controlled trial.2011
Two-year outcomes for children with autism after the cessation of early intensive behavioral intervention.
Outcomes of behavioral intervention for children with autism in mainstream pre-school settings.2012
Improving emotion regulation with CBT in young children with high functioning autism spectrum disorders: a pilot study.2011
A randomized controlled trial of Hanen's 'More Than Words' in toddlers with early autism symptoms.2011
Intervention targeting development of socially synchronous engagement in toddlers with autism spectrum disorder: a randomized controlled trial.2011
The efficacy of a Social Skills Group Intervention for improving social behaviors in children with High Functioning Autism Spectrum disorders.2011
Low intensity behavioral treatment supplementing preschool services for young children with autism spectrum disorders and severe to mild intellectual disability.-- Not Found --
Effects of cognitive behavioral therapy on daily living skills in children with high-functioning autism and concurrent anxiety disorders.2011
Randomized controlled trial of the focus parent training for toddlers with autism: 1-year outcome.2010
RCT of a manualized social treatment for high-functioning autism spectrum disorders.2010
Promoting social skill development in children with pervasive developmental disorders: a feasibility and efficacy study.2010
Early behavioral intervention is associated with normalized brain activity in young children with autism.2012
Effects of risperidone and parent training on adaptive functioning in children with pervasive developmental disorders and serious behavioral problems.2012
Predictors and moderators of parent training efficacy in a sample of children with autism spectrum disorders and serious behavioral problems.
Effects of a standardized pamphlet on insomnia in children with autism spectrum disorders.
The inclusion of siblings in social skills training groups for boys with Asperger syndrome.2011
A randomized controlled trial of preschool-based joint attention intervention for children with autism.2012
Long-term outcomes of toddlers with autism spectrum disorders exposed to short-term intervention.2012
Using the transporters DVD as a learning tool for children with Autism Spectrum Disorders (ASD).2012
Brief report: effect of a focused imitation intervention on social functioning in children with autism.
Teacher-implemented joint attention intervention: pilot randomized controlled study for preschoolers with autism.
Learning through interaction in children with autism: preliminary data from asocial-communication-based intervention.2013
A randomized trial comparison of the effects of verbal and pictorial naturalistic communication strategies on spoken language for young children with autism.2014
Randomized controlled effectiveness trial of executive function intervention for children on the autism spectrum.2014
See what I see, do as I do: Promoting joint attention and imitation in preschoolers with autism spectrum disorder.
The Autism MEAL Plan: A parent-training curriculum to manage eating aversions and low intake among children with autism.2013
TEACCH-based group social skills training for children with high-functioning autism: a pilot randomized controlled trial.2013
Long-term outcomes of parent-assisted social skills intervention for high-functioning children with autism spectrum disorders.2014
The impact of parent-delivered intervention on parents of very young children with autism.2014
Parent-based sleep education for children with autism spectrum disorders.2014
Use of a Direct Observational Measure in a Trial of Risperidone and Parent Training in Children with Pervasive Developmental Disorders.2013
Neurofeedback Improves Executive Functioning in Children with Autism Spectrum Disorders
Impact of Severity of Autism and Intervention Time-Input on Child Outcomes: Comparison across Several Early Interventions
Brief Report: Longitudinal Improvements in the Quality of Joint Attention in Preschool Children with Autism
Outcome for Children with Autism Receiving Early and Intensive Behavioral Intervention in Mainstream Preschool and Kindergarten Settings
Randomized, Controlled Trial of the Leap Model of Early Intervention for Young Children with Autism Spectrum Disorders
Who Benefits from Early Intervention in Autism Spectrum Disorders?
The Effectiveness of a Cross-Setting Complementary Staff- and Parent-Mediated Early Intensive Behavioral Intervention for Young Children with ASD
A Randomised Controlled Trial of Two Early Intervention Programs for Young Children with Autism: Centre-Based with Parent Program and Home-Based
Preschoolers with Autism Spectrum Disorders: Evaluating the Impact of a Home-Based Intervention to Promote Their Communication
Treatment Approach, Autism Severity and Intervention Outcomes in Young Children
Effects of a brief Early Start Denver Model (ESDM)–based parent intervention on toddlers at risk for autism spectrum disorders: A randomized controlled trial
Randomized controlled trial for early intervention for autism: A pilot study of the Autism 1-2-3 project
Randomized controlled caregiver mediated joint engagement intervention for toddlers with autism
Brief report: Pilot randomized controlled trial of reciprocal imitation training for teaching elicited and spontaneous imitation to children with autism
The effects of a parent-focused intervention for children with a recent diagnosis of autism spectrum disorder on parenting stress and competence
Long-term effects of neurofeedback treatment in autism
Neurofeedback treatment in autism. Preliminary findings in behavioral, cognitive, and neurophysiological functioning
The relationship between parental stress and intervention outcome of children with autism
Theory of mind training in children with autism: A randomized controlled trial
Picture Me Playing: Increasing Pretend Play Dialogue of Children with Autism Spectrum Disorders
Predictors of Outcome for Children Receiving Intensive Behavioral Intervention in a Large, Community-Based Program
Research units of pediatric psychopharmacology (RUPP) autism network randomized clinical trial of parent training and medication: One-year follow-Up
Controlled‐release melatonin, singly and combined with cognitive behavioural therapy, for persistent insomnia in children with autism spectrum disorders: A randomized placebo‐controlled trial
Effectiveness of large-scale community-based intensive Behavioral Intervention: A waitlist comparison study exploring outcomes and predictors
A preliminary randomized controlled trial of two social skills interventions for youth with high-functioning autism spectrum disorders
Randomized clinical trial replication of a psychosocial treatment for children with high‐functioning autism spectrum disorders
Increasing Verbal Responsiveness in Parents of Children with Autism: A Pilot Study
Outcomes of intensive behavioural intervention in the Toronto Preschool Autism Service
The Coping Cat program for children with anxiety and autism spectrum disorder: A pilot randomized controlled trial
A Parent-Mediated Intervention to Increase Responsive Parental Behaviors and Child Communication in Children with ASD: A Randomized Clinical Trial
The effect of cognitive-behavioral therapy versus treatment as usual for anxiety in children with autism spectrum disorders: A randomized, controlled trial
Teaching Emotion Recognition Skills to Young Children with Autism: A Randomised Controlled Trial of an Emotion Training Programme
Mediation of treatment effect in a communication intervention for pre-school children with autism
Preschool Based JASPER Intervention in Minimally Verbal Children with Autism: Pilot RCT
Intensive cognitive behavioral therapy for anxiety disorders in school-aged children with autism: A preliminary comparison with treatment-as-usual
Further Evidence of Benefits of Thought-Bubble Training for Theory of Mind Development in Children with Autism Spectrum Disorders
The relative importance of age and IQ as predictors of outcomes in Intensive Behavioral Intervention
Effectiveness of low intensity behavioral treatment for children with autism spectrum disorder and intellectual disability
Evaluation of the Barnet Early Autism Model (BEAM) Teaching Intervention Programme in a "Real World" Setting
Effects of Joint Attention Mediated Learning for Toddlers with Autism Spectrum Disorders: An Initial Randomized Controlled Study
A play and joint attention intervention for teachers of young children with Autism: A randomized controlled pilot study

Downloadable Data Content

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