Procedures for Managing Postpartum Hemorrhage: A Systematic Review

Project Summary Title and Description

Procedures for Managing Postpartum Hemorrhage: A Systematic Review
Authors of Report
Methodology description
Funding Source

Key Questions

1. What is the evidence for the comparative effectiveness of interventions for management of postpartum hemorrhage? a. What is the comparative effectiveness of interventions intended to treat postpartum hemorrhage likely due to atony? b. What is the comparative effectiveness of interventions intended to treat postpartum hemorrhage likely due to retained placenta? c. What is the comparative effectiveness of interventions intended to treat postpartum hemorrhage likely due to genital tract trauma? d. What is the comparative effectiveness of interventions intended to treat postpartum hemorrhage likely due to uncommon causes (e.g., coagulopathies, uterine inversion, subinvolution)?
2. What is the evidence for choosing one intervention over another and when to proceed to subsequent interventions for management of postpartum hemorrhage?
3. What are the comparative harms, including adverse events, associated with interventions for management of postpartum hemorrhage?
4. What is the comparative effectiveness of interventions to treat acute blood loss anemia after stabilization of postpartum hemorrhage?
5. What systems-level interventions are effective in improving management of postpartum hemorrhage?

Associated Extraction Forms

Associated Studies (each link opens a new tab)

Practices for prevention, diagnosis and management of postpartum haemorrhage: impact of a regional multifaceted intervention2009
Multifacetedinterventiontodecreasetherateofseverepostpartumhaemorrhage: thePITHAGORE6cluster-randomisedcontrolledtrial2010
High-dosetranexamic acidreducesblood lossinpostpartum haemorrhage.2011
Successfulreductionofmassivepostpartumhaemorrhageby use ofguidelinesandstaffeducation.2004
Improvinghospitalsystemsfor thecareofwomenwithmajorobstetrichemorrhage.2006
The efficacy of fibrinogen concentrate compared with cryoprecipitate in major obstetric haemorrhage--an observational study2012
An open non-randomized study of recombinant activated factor VII in major postpartum haemorrhage2007
Whole blood in the management of hypovolemia due to obstetric hemorrhage2009
Use of recombinant activated factor VII in primary postpartum hemorrhage: the Northern European registry 2000-20042007
Efficacy of rectal misoprostol as second-line therapy for the treatment of primary postpartum hemorrhage2008
Transfusion practices in postpartum hemorrhage: a population-based study2013
Analysis of the venous thromboembolic risk associated with severe postpartum haemorrhage in the NOHA First cohort2008
Serious primary post-partum hemorrhage, arterial embolization and future fertility: a retrospective study of 46 cases2008
Initial experience with a dual-balloon catheter for the management of postpartum hemorrhage2014
Surgical versus medical treatment for secondary post-partum hemorrhage2009
Impact of pelvic arterial embolization for intractable postpartum hemorrhage on fertility2009
Menses recovery and fertility after artery embolization for PPH: a single-center retrospective observational study2009
Uterine artery embolization in the treatment of postpartum uterine hemorrhage2011
Predictive factors of advanced interventional procedures in a multicentre severe postpartum haemorrhage study2011
Peripartum hysterectomy: 1999 to 20062008
Secondary postpartum haemorrhage: incidence, morbidity and current management2001
Specific second-line therapies for postpartum haemorrhage: a national cohort study2011
Uterine compression sutures for the management of severe postpartum hemorrhage2011
Failed pelvic arterial embolization for postpartum hemorrhage: clinical outcomes and predictive factors2013
Peripartum hysterectomy in the UK: management and outcomes of the associated haemorrhage2007
Trends in the rate of invasive procedures after the addition of the intrauterine tamponade test to a protocol for management of severe postpartum hemorrhage2012
Changes in care associated with the introduction of a postpartum hemorrhage patient safety program2013
Usefulness of pelvic artery embolization in cesarean section compared with vaginal delivery in 176 patients2013
Primary postpartum hemorrhage: outcome of pelvic arterial embolization in 251 patients at a single institution2012
Risk factors and management patterns for emergency obstetric hysterectomy over 2 decades2010
Evaluation of multi-professional obstetric skills training for postpartum hemorrhage2012
Use of recombinant factor VIIa in massive post-partum haemorrhage2008
Uterine artery ligation in the control of postcesarean hemorrhage1995
Controlling refractory atonic postpartum hemorrhage with Hemabate sterile solution1990
Efficacy of surgical techniques to control obstetric hemorrhage: analysis of 539 cases2011
Recombinant activated factor VII in obstetric hemorrhage: experiences from the Australian and New Zealand Haemostasis Registry2009
Predictive factors for failure of pelvic arterial embolization for postpartum hemorrhage2012
Peripartum hysterectomy in Denmark 1995-20042007
Prostaglandin E2 analogue sulprostone for treatment of atonic postpartum hemorrhage2011
Long-term psychological impact of severe postpartum hemorrhage2011
Predictors of failed pelvic arterial embolization for severe postpartum hemorrhage2009
Fertility and pregnancy following pelvic arterial embolisation for postpartum haemorrhage2010
Comprehensive maternal hemorrhage protocols improve patient safety and reduce utilization of blood products2011
An increase in initial shock index is associated with the requirement for massive transfusion in emergency department patients with primary postpartum hemorrhage2013
Efficacy of recombinant human soluble thrombomodulin in severe postpartum hemorrhage with disseminated intravascular coagulation2013
Efficacy of selective arterial embolisation for the treatment of life-threatening post-partum haemorrhage in a large population2008
Regionalization of care for obstetric hemorrhage and its effect on maternal mortality2010
Peripartum hysterectomy and arterial embolization for major obstetric hemorrhage: a 2-year nationwide cohort study in the Netherlands2010
The factors associated with the failure of transcatheter pelvic arterial embolization for intractable postpartum hemorrhage2014
Methylergonovine maleate and the risk of myocardial ischemia and infarction2013
Intravenous iron sucrose versus oral iron ferrous sulfate for antenatal and postpartum iron deficiency anemia: a randomized trial2013
Transfusion policy after severe postpartum haemorrhage: a randomised non-inferiority trial2014
Management in intractable obstetric haemorrhage: an audit study on 61 cases2001
Fertility after embolization of the uterine arteries to treat obstetrical hemorrhage: a review of 53 cases2010
Uterine artery embolization for primary postpartum hemorrhage2013
Clinical audit: a useful tool for reducing severe postpartum haemorrhages?2011
Outcomes of subsequent pregnancies after uterine compression sutures for postpartum hemorrhage.2013
Blood transfusion for primary postpartum hemorrhage: a tertiary care hospital review.2008
Uterine-sparing surgical management of postpartum hemorrhage: is it always effective?2012
Use of second-line therapies for management of massive primary postpartum hemorrhage.2013
Emergency peripartum hysterectomy: a comparison of cesarean and postpartum hysterectomy.2004
Use of Bakri balloon tamponade in the treatment of postpartum hemorrhage: a series of 50 cases from a tertiary teaching hospital.2013
Emergency Obstetric Hysterectomies (How Many Are Potentially Preventable?): A 28-Year Experience in Saskatoon2004
Does a postpartum hemorrhage patient safety program result in sustained changes in management and outcomes?
Transcatheter arterial embolization for secondary postpartum hemorrhage: outcome in 52 patients at a single tertiary referral center.2014
Severe postpartum haemorrhage after vaginal delivery: a statistical process control chart to report seven years of continuous quality improvement.2014
Outcome of pelvic arterial embolization for postpartum hemorrhage: A retrospective review of 117 cases.2014
Subsequent pregnancy outcome after B-lynch suture placement.
Comprehensive maternal hemorrhage protocols reduce the use of blood products and improve patient safety.2014
Use of an intrauterine inflated catheter balloon in massive post-partum hemorrhage: a series of 52 cases.2014
Efficacy of transarterial embolisation in the management of post-partum haemorrhage and its impact on subsequent pregnancies.2014
Introduction of an algorithm for ROTEM-guided fibrinogen concentrate administration in major obstetric haemorrhage.2015
Acute lung injury complicating blood transfusion in post-partum hemorrhage: incidence and risk factors.2014

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