Tympanostomy Tubes in Children
Project Summary Title and Description
- Tympanostomy Tubes in Children
- Authors of Report
- Methodology description
- Data sources. We conducted literature searches in MEDLINE®, the Cochrane Central Trials Registry and Cochrane Database of Systematic Reviews, Embase®, and CINAHL®. Additionally, we perused the reference lists of published relevant clinical practice guidelines and narrative and systematic reviews, and examined Scientific Information Packages from manufacturers. Citations were independently screened by two researchers. Review methods. Each study was extracted by one methodologist and confirmed by at least one other methodologist. Data were extracted into customized forms in the Systematic Review Data Repository (SRDR) online system. All included studies were summarized in narrative form and in summary tables. We conducted random effects meta-analyses of comparative studies that were sufficiently similar in population, interventions, and outcomes, and network meta-analyses to compare treatment alternatives across studies. Specific methods and metrics (summary measures) meta-analyzed were chosen based on available reported study data.
- Report PMID: 28817250 Data was entered prospectively.
- Funding Source
- This report is based on research conducted by the Brown Evidence-based Practice Center (EPC) under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (Contract No. 290-2015-00002-I).
- 1. For children with chronic otitis media with effusion, what is the effectiveness of tympanostomy tubes, compared to watchful waiting, on resolution of middle ear effusion, hearing and vestibular outcomes, quality of life and other patient-centered outcomes? a. What factors (such as age, age of onset, duration of effusion, comorbidities, and sociodemographic risk factors) predict which children are likely to benefit most from the intervention? b. Does obtaining a hearing test help identify which children are more likely to benefit from the intervention?
- 2. For children with recurrent acute otitis media, what is the effectiveness of tympanostomy tubes, compared to watchful waiting with episodic or prophylactic antibiotic therapy, on the frequency and severity of otitis media, quality of life, and other patient centered-outcomes? What factors (such as age, age of onset, number of recurrences, presence of persistent middle ear effusion, comorbidities, and sociodemographic risk factors, history of complications of acute otitis media, antibiotic allergy or intolerance) identify children who are most likely to benefit from the intervention?
- 3. What adverse events, surgical complications, and sequelae are associated with inserting tympanostomy tubes in children with either chronic otitis media with effusion or recurrent acute otitis media?
- 4. Do water precautions reduce the incidence of tympanostomy tube otorrhea, or affect quality of life?
- 5. In children with tympanostomy tube otorrhea, what is the comparative effectiveness of topical antibiotic drops versus systemic antibiotics or watchful waiting on duration of otorrhea, quality of life, or need for tube removal?
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Downloadable Data Content
- XLSX Project Data