Project Summary Title and Description

Authors of Report
Methodology description
Funding Source

Key Questions

1. What are the outcome domains in clinical trials included in Cochrane reviews on cataract, glaucoma, age-related macular degeneration, and diabetic retinopathy?

Associated Extraction Forms

Associated Studies (each link opens a new tab)

Six-year supplementation with alpha-tocopherol and beta-carotene and age-related maculopathy.1998
Beta carotene supplementation and age-related maculopathy in a randomized trial of US physicians.2007
Vitamin E supplementation and macular degeneration: randomised controlled trial.2002
Vitamin E and age-related macular degeneration in a randomized trial of women.2010
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
Effect of lutein and antioxidant dietary supplementation on contrast sensitivity in age-related macular disease: a randomized controlled trial.2007
Carotenoids in Age-related Maculopathy Italian Study (CARMIS): two-year results of a randomized study.2012
Effects of lutein supplementation on macular pigment optical density and visual acuity in patients with age-related macular degeneration.2011
Oral zinc in macular degeneration.
A randomized, prospective, placebo-controlled clinical trial of a novel zinc-monocysteine compound in age-related macular degeneration.2008
Oral zinc and the second eye in age-related macular degeneration.1996
Methodology of the VECAT study: vitamin E intervention in cataract and age-related maculopathy.1999
Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial).2004
Laser treatment in patients with bilateral large drusen: the complications of age-related macular degeneration prevention trial.2006
Laser-induced drusen reduction improves visual function at 1 year. Choroidal Neovascularization Prevention Trial Research Group.1999
Prophylactic laser treatment hastens choroidal neovascularization in unilateral age-related maculopathy: final results of the drusen laser study.2006
Laser photocoagulation for macular soft drusen. Updated results.1997
Prophylactic laser treatment in early age related maculopathy reduced the incidence of exudative complications.
Anecortave acetate as monotherapy for treatment of subfoveal neovascularization in age-related macular degeneration: twelve-month clinical outcomes.2003
Prophylactic laser treatment of soft drusen maculopathy: a prospective, randomized Nordic study.2009
Therapeutic benefits of infrared (810-nm) diode laser macular grid photocoagulation in prophylactic treatment of nonexudative age-related macular degeneration: two-year results of a randomized pilot study.1999
Indirect scatter laser photocoagulation to subfoveal choroidal neovascularization in age-related macular degeneration.1997
Phacoemulsification versus extracapsular cataract extraction in patients with diabetes.2000
Intravitreal bevacizumab for prevention of early postvitrectomy hemorrhage in diabetic patients: a randomized clinical trial.2009
The effect of adjunctive intravitreal bevacizumab for preventing postvitrectomy hemorrhage in proliferative diabetic retinopathy.2011
Role of combined cataract surgery and intravitreal bevacizumab injection in preventing progression of diabetic retinopathy: prospective randomized study.2009
Intravitreal triamcinolone and bevacizumab as adjunctive treatments to panretinal photocoagulation in diabetic retinopathy.2010
Intravitreal bevacizumab for surgical treatment of severe proliferative diabetic retinopathy.2010
Prophylactic treatment of age-related macular degeneration report number 2: 810-nanometer laser to eyes with drusen: bilaterally eligible patients.2009
Prophylactic treatment of age-related macular degeneration report number 1: 810-nanometer laser to eyes with drusen. Unilaterally eligible patients.
Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial.2013
Oral docosahexaenoic acid in the prevention of exudative age-related macular degeneration: the Nutritional AMD Treatment 2 study.
Randomized clinical trial evaluating intravitreal ranibizumab or saline for vitreous hemorrhage from proliferative diabetic retinopathy.
Interferon alfa-2a is ineffective for patients with choroidal neovascularization secondary to age-related macular degeneration. Results of a prospective randomized placebo-controlled clinical trial. Pharmacological Therapy for Macular Degeneration Study Group.
A randomized controlled clinical trial on the efficacy of radiation therapy in the control of subfoveal choroidal neovascularization in age-related macular degeneration: radiation versus observation.1998
A randomized clinical trial of a single dose of intravitreal triamcinolone acetonide for neovascular age-related macular degeneration: one-year results.2003
Anecortave acetate (15 milligrams) versus photodynamic therapy for treatment of subfoveal neovascularization in age-related macular degeneration.2006
Intravitreal bevacizumab as an adjunctive therapy before diabetic vitrectomy.2008
Ranibizumab versus verteporfin for neovascular age-related macular degeneration.2006
Pegaptanib 1-year systemic safety results from a safety-pharmacokinetic trial in patients with neovascular age-related macular degeneration.
Surgery for hemorrhagic choroidal neovascular lesions of age-related macular degeneration: ophthalmic findings: SST report no. 13.2004
Quality of life in patients with age-related macular degeneration: results from the VISION study.2008
Ranibizumab combined with verteporfin photodynamic therapy in neovascular age-related macular degeneration: year 1 results of the FOCUS Study.2006
Intravitreal bevacizumab versus panretinal photocoagulation for treatment-naı¨ve proliferative and severe nonproliferative diabetic retinopathy2012
Improved vision-related function after ranibizumab treatment of neovascular age-related macular degeneration: results of a randomized clinical trial.2007
Macular scatter ('grid') laser treatment of poorly demarcated subfoveal choroidal neovascularization in age-related macular degeneration. Results of a randomized pilot trial.1996
Preoperative injection of intravitreal bevacizumab in dense diabetic vitreous hemorrhage.-- Not Found --
Intravitreal injection of pegaptanib sodium for proliferative diabetic retinopathy.2009
Bevacizumab-augmented retinal laser photocoagulation in proliferative diabetic retinopathy: a randomized double-masked clinical trial.
Bevacizumab-augmented retinal laser photocoagulation in proliferative diabetic retinopathy: a randomized double-masked clinical trial.-- Not Found --
Panretinal photocoagulation (PRP) versus PRP plus intravitreal ranibizumab for high-risk proliferative diabetic retinopathy.2011
Injection of intravitreal bevacizumab (Avastin) as a preoperative adjunct before vitrectomy surgery in the treatment of severe proliferative diabetic retinopathy (PDR).2008
Argon green vs krypton red laser photocoagulation of extrafoveal choroidal neovascular lesions. One-year results in age-related macular degeneration. The Canadian Ophthalmology Study Group.1993
Grid laser treatment of occult choroidal neovascularization in age related macular degeneration.1993
Perifoveal laser treatment for subfoveal choroidal new vessels in age-related macular degeneration. Results of a randomized clinical trial.
Treatment of senile disciform macular degeneration: a single-blind randomised trial by argon laser photocoagulation. The Moorfields Macular Study Group.1982
Argon laser photocoagulation for senile macular degeneration. Results of a randomized clinical trial.1982
Krypton laser photocoagulation for neovascular lesions of age-related macular degeneration. Results of a randomized clinical trial. Macular Photocoagulation Study Group.1990
Laser photocoagulation of subfoveal neovascular lesions in age-related macular degeneration. Results of a randomized clinical trial. Macular Photocoagulation Study Group.
Laser photocoagulation of subfoveal recurrent neovascular lesions in age-related macular degeneration. Results of a randomized clinical trial. Macular Photocoagulation Study Group.1991
Submacular surgery trials randomized pilot trial of laser photocoagulation versus surgery for recurrent choroidal neovascularization secondary to age-related macular degeneration: I. Ophthalmic outcomes submacular surgery trials pilot study report number 1.2000
Argon laser treatment of pigment epithelial detachments and of subretinal neovascular membranes in Junius-Kuhnt's senile disciform macular degeneration. A prospective, randomized study.1982
Treatment of neovascular senile maculopathy at the foveal capillary free zone with red krypton laser.1982
Angiofibrotic response to vascular endothelial growth factor inhibition in diabetic retinal detachment: report no. 1.2012
Intravitreal Avastin as an adjunct in patients with proliferative diabetic retinopathy undergoing pars plana vitrectomy.2013
Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and strokes.2002
Effect of blood pressure control on diabetic microvascular complications in patients with hypertension and type 2 diabetes.2000
Effects of medical therapies on retinopathy progression in type 2 diabetes.2010
Effects of blood pressure lowering and intensive glucose control on the incidence and progression of retinopathy in patients with type 2 diabetes mellitus: a randomised controlled trial.2009
Effect of trandolapril on regression of retinopathy in hypertensive patients with type 2 diabetes: a prespecified analysis of the benedict trial.2010
Effects of manidipine and delapril in hypertensive patients with type 2 diabetes mellitus: the delapril and manidipine for nephroprotection in diabetes (DEMAND) randomized clinical trial.2011
Effect of lisinopril on progression of retinopathy in normotensive people with type 1 diabetes. The EUCLID Study Group. EURODIAB Controlled Trial of Lisinopril in Insulin-Dependent Diabetes Mellitus.1998
Angiotensin-converting enzyme inhibition for the treatment of moderate to severe diabetic retinopathy in normotensive Type 2 diabetic patients. A pilot study.-- Not Found --
Renal and retinal effects of enalapril and losartan in type 1 diabetes.2009
Intensified multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: the Steno type 2 randomised study.1999
Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group.1998
Early photocoagulation for diabetic retinopathy. ETDRS report number 9. Early Treatment Diabetic Retinopathy Study Research Group.1991
Peripheral retinal ablation in the treatment of proliferative diabetic retinopathy: a three-year interim report of a randomised, controlled study using the argon laser.1977
Multicenter randomized clinical trial of retinal photocoagulation for preproliferative diabetic retinopathy.2012
Optic disc neovascularisation in diabetic retinopathy: II. Natural history and results of photocoagulation treatment.1980
The Antioxidants in Prevention of Cataracts Study: effects of antioxidant supplements on cataract progression in South India.2006
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9.2001
Incidence of cataract operations in Finnish male smokers unaffected by alpha tocopherol or beta carotene supplements.1998
A randomized trial of beta carotene and age-related cataract in US physicians.2003
Age-related cataract in a randomized trial of vitamins E and C in men.2010
The Roche European American Cataract Trial (REACT): a randomized clinical trial to investigate the efficacy of an oral antioxidant micronutrient mixture to slow progression of age-related cataract.2002
Vitamin E supplementation and cataract: randomized controlled trial.2004
Vitamin E and age-related cataract in a randomized trial of women.2008
Outcomes and costs of outpatient and inpatient cataract surgery: a randomised clinical trial.2001
Postoperative inflammation: extracapsular cataract extraction versus phacoemulsification.1999
Comparison of endothelial cell loss and surgically induced astigmatism following conventional extracapsular cataract surgery, manual small-incision surgery and phacoemulsification.2005
Epidemiological feasibility of cardiovascular primary prevention in general practice: a trial of vitamin E and aspirin. Collaborative group of the Primary Prevention Project.1995
Safety and efficacy of phacoemulsification compared with manual small-incision cataract surgery by a randomized controlled clinical trial: six-week results.2005
Comparing phacoemulsification and extracapsular cataract extraction in eyes with pseudoexfoliation syndrome, small pupil, and phacodonesis.2004
Randomised controlled trial of anterior-chamber intraocular lenses.1997
Ultrasound biomicroscopy examination of intraocular lens haptic position after phacoemulsification with continuous curvilinear capsulorhexis and extracapsular cataract extraction with linear capsulotomy.1999
Randomized study of the blood-aqueous barrier reaction after phacoemulsification and extracapsular cataract extraction.1998
Effect of cataract surgery on the corneal endothelium: modern phacoemulsification compared with extracapsular cataract surgery.2004
The Madurai Intraocular Lens Study. II: Clinical outcomes.1998
Cataract surgery: interim results and complications of a randomised controlled trial. Oxford Cataract Treatment and Evaluation Team (OCTET).1986
Extracapsular cataract surgery compared with manual small incision cataract surgery in community eye care setting in western India: a randomised controlled trial.2003
Corneal endothelial function after extracapsular cataract extraction and phacoemulsification.1997
Cost analysis of cataract surgery with intraocular lens implantation: a single blind randomised clinical trial comparing extracapsular cataract extraction and phacoemulsification.2003
The South Asian cataract management study: complications, vision outcomes, and corneal endothelial cell loss in a randomized multicenter clinical trial comparing intracapsular cataract extraction with and without anterior chamber intraocular lens implantation.2000
A comparison of anterior and posterior chamber lenses after cataract extraction in rural Africa: a within patient randomised trial.
Endothelial damage with cataract surgery techniques.
Phacoemulsification versus extracapsular extraction: governmental costs.2010
Functional assessment of two different accommodative intraocular lenses compared with a monofocal intraocular lens.2007
A prospective, comparative study between endoscopic cyclophotocoagulation and the Ahmed drainage implant in refractory glaucoma.2004
Partial Tenon's capsule resection with adjunctive mitomycin C in Ahmed glaucoma valve implant surgery.2003
Randomized comparison of 1-Site and 2-Site phacotrabeculectomy with 3-year follow-up.
A prospective randomized trial comparing intraoperative 5-fluorouracil vs mitomycin C in primary trabeculectomy.
Fellow eye comparison between the 1CU accommodative intraocular lens and the Acrysof MA30 monofocal intraocular lens.2005
Potential of the 1 CU accommodative intraocular lens.
Visual outcome of conventional extracapsular cataract extraction with posterior chamber intraocular lens implantation versus manual small-incision cataract surgery.-- Not Found --
Phaco-emulsification versus manual small-incision cataract surgery in South Africa.2012
Prospective randomized comparative study of macular thickness following phacoemulsification and manual small incision cataract surgery.2010
Comparison of endothelial cell loss after cataract surgery: phacoemulsification versus manual small-incision cataract surgery: six-week results of a randomized control trial.
A prospective randomized clinical trial of phacoemulsification vs manual sutureless small-incision extracapsular cataract surgery in Nepal.2007
Phacoemulsification versus small incision cataract surgery (SICS): which one is a better surgical option for immature cataract in developing countries?-- Not Found --
Phacoemulsification versus manual small-incision cataract surgery for white cataract.2010
Randomised clinical trial of lensectomy versus lens aspiration and primary capsulotomy for children with bilateral cataract in south India.1999
Morphological and functional results of AcrySof intraocular lens implantation in children: prospective randomized study of age-related surgical management.2003
Posterior continuous curvilinear capsulorhexis with and without optic capture of the posterior chamber intraocular lens in the absence of vitrectomy.-- Not Found --
Necessity of vitrectomy when optic capture is performed in children older than 5 years.2001
Are routine preoperative medical tests needed with cataract surgery?2001
The value of routine preoperative medical testing before cataract surgery
Quality of life evaluation after implantation of 2 multifocal intraocular lens models and a monofocal model.2011
One-year outcomes with new-generation multifocal intraocular lenses.2008
Contrast sensitivity after implantation of diffractive bifocal and monofocal intraocular lenses.1998
Comparing the 1CU accommodative, multifocal, and monofocal intraocular lenses: a randomized trial.2008
Cataract extraction with multifocal intraocular lens implantation: a multinational clinical trial evaluating clinical, functional, and quality-of-life outcomes.2000
Comparison of the Binocular Vision Quality After Implantation of Monofocal and Multifocal Intraocular Lenses2011
Contrast sensitivity and depth of focus with aspheric multifocal versus conventional monofocal intraocular lens.2001
Prospective randomised double-masked trial of bilateral multifocal, bifocal or monofocal intraocular lenses.2002
Comparative performance of intraocular lenses in eyes with cataract and uveitis.2002
Biocompatibility and blood-aqueous barrier impairment in at-risk eyes with heparin-surface-modified or unmodified lenses.1998
Uveal and capsular biocompatibility of two foldable acrylic intraocular lenses in patients with endogenous uveitis--a prospective randomized study.2008
Heparin surface-modified intraocular lenses in patients with inactive uveitis or diabetes.1998
Effect of diclofenac versus dexamethasone on posterior capsule opacification.
Effect of 1-piece and 3-piece AcrySof intraocular lenses on the development of posterior capsule opacification after cataract surgery.2004
Effect of anterior capsule polishing on the posterior capsule opacification-inhibiting properties of a sharp-edged, 3-piece, silicone intraocular lens: three- and 5-year results of a randomized trial.2006
Effect of an acrylic intraocular lens with a sharp posterior optic edge on posterior capsule opacification.2002
Effect of a silicone intraocular lens with a sharp posterior optic edge on posterior capsule opacification.2004
Long-term effect of optic edge design in an acrylic intraocular lens on posterior capsule opacification.2005
Long-term effect of optic edge design in a silicone intraocular lens on posterior capsule opacification.2007
Fellow-eye comparison of posterior capsule opacification with AcrySof SN60AT and AF-1 YA-60BB blue-blocking intraocular lenses.2008
Inhibition of posterior capsule opacification with an immunotoxin specific for lens epithelial cells: 24 month clinical results.1998
Randomized intraindividual comparison of posterior capsule opacification between a microincision intraocular lens and a conventional intraocular lens.2009
Long-term effect of sharp optic edges of a polymethyl methacrylate intraocular lens on posterior capsule opacification: a randomized trial.2005
Effect of optic material on posterior capsule opacification in intraocular lenses with sharp-edge optics: randomized clinical trial.2005
Incidence of postoperative posterior capsular opacification following treatment with diclofenac 0.1% and ketorolac 0.5% ophthalmic solutions: 3-year randomized, double-masked, prospective clinical investigation.2000
Fellow-eye comparison of posterior capsule opacification rates after implantation of 1CU accommodating and AcrySof MA30 monofocal intraocular lenses.2007
Quantitative comparison of posterior capsule opacification after polymethylmethacrylate, silicone, and soft acrylic intraocular lens implantation.1998
Posterior capsule opacification after implantation of a hydrogel intraocular lens.2004
Posterior capsule opacification in the presence of an intraocular lens with a sharp versus rounded optic edge.2005
Influence on posterior capsule opacification and visual function of intraocular lens optic material.2007
Comparison of posterior capsule opacification rates between hydrophilic and hydrophobic single-piece acrylic intraocular lenses.2005
Lens epithelial cell regression on the posterior capsule with different intraocular lens materials.1998
The effect of capsulorhexis size on posterior capsular opacification: one-year results of a randomized prospective trial.1999
Posterior capsular opacification with hydrogel, polymethylmethacrylate, and silicone intraocular lenses: two-year results of a randomized prospective trial.2000
Optic edge design as long-term factor for posterior capsular opacification rates.2008
Posterior capsule opacification after implantation of a hydrophilic or a hydrophobic acrylic intraocular lens: one-year follow-up.2006
Posterior capsule opacification 3 years after implantation of an AcrySof and a MemoryLens in fellow eyes.2000
Effects of dexamethasone, diclofenac, or placebo on the inflammatory response after cataract surgery.2002
Effectiveness of multifocal intraocular lenses to correct presbyopia after cataract surgery: a randomized controlled trial.
Visual function with bilateral implantation of monofocal and multifocal intraocular lenses: a prospective, randomized, controlled clinical trial.2008
Quality of vision after AMO Array multifocal intraocular lens implantation.2004
Visual function after monocular implantation of apodized diffractive multifocal or single-piece monofocal intraocular lens Randomized prospective comparison.2010
Long-term effect of 1-piece and 3-piece hydrophobic acrylic intraocular lens on posterior capsule opacification: a randomized trial.2007
Heparin eyedrops to prevent posterior capsule opacification.1997
Double-masked prospective ocular safety study of a lens epithelial cell antibody to prevent posterior capsule opacification.2000
Effect of intraocular lens haptic compressibility on the posterior lens capsule after cataract surgery.2001
Efficacy and safety of capsular bending ring implantation to prevent posterior capsule opacification: three-year results of a randomized clinical trial.2008
Posterior capsule opacification after implantation of CeeOn Edge 911A, PhacoFlex SI-40NB, and AcrySof MA60BM lenses: one-year results of an intraindividual comparison multicenter study.2004
A prospective, randomised comparison of single and three piece acrylic foldable intraocular lenses.2004
Prospective intrapatient comparison of 6.0-millimeter optic single-piece and 3-piece hydrophobic acrylic foldable intraocular lenses.2006
Posterior capsule opacification after phacoemulsification: silicone CeeOn Edge versus acrylate AcrySof intraocular lens.
Long-term results of sealed capsule irrigation using distilled water to prevent posterior capsule opacification: a prospective clinical randomised trial.2007
Comparison of posterior capsule opacification between the 1-piece and 3-piece Acrysof intraocular lenses: two-year results of a randomized trial.2004
Effect of anterior capsule polishing on fibrotic capsule opacification: three-year results.2004
Influence of optic edge design and anterior capsule polishing on posterior capsule fibrosis.2004
Effect of intraocular lens optic edge design and material on fibrotic capsule opacification and capsulorhexis contraction.2004
Long-term efficacy of adding a sharp posterior optic edge to a three-piece silicone intraocular lens on capsule opacification: five-year results of a randomized study.2005
Effect of intraocular lens edge profile on posterior capsule opacification after extracapsular cataract surgery in a developing country.2007
Posterior capsule opacification after extra capsular cataract extraction in Indian rural population: foldable acrylic vs poly (methyl-methacrylate) intraocular lenses a randomized clinical trial.2008
Three-year follow-up of posterior capsule opacification with two different silicone intraocular lenses.2005
Three-year prospective randomized study of incidence of posterior capsule opacification in eyes treated with topical diclofenac and betamethasone.2003
Anterior capsule relationship of the AcrySof intraocular lens optic and posterior capsule opacification: a prospective randomized clinical trial.2004
Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: one-year results of 2 randomized clinical trials--TAP report. Treatment of age-related macular degeneration with photodynamic therapy (TAP) Study Group.
Verteporfin therapy of subfoveal choroidal neovascularization in age-related macular degeneration: two-year results of a randomized clinical trial including lesions with occult with no classic choroidal neovascularization--verteporfin in photodynamic therapy report 2.2001
The age-related macular degeneration radiotherapy trial (AMDRT): one year results from a pilot study.2004
Randomized trial of radiation for age-related macular degeneration.1999
Proton therapy for exudative age-related macular degeneration: a randomized, sham-controlled clinical trial.2002
Radiotherapy for age-related macular degeneration: is there a benefit for classic CNV?2001
Strontium plaque brachytherapy for exudative age-related macular degeneration: three-year results of a randomized study.2005
Age-related macular degeneration: long-term results of radiotherapy for subfoveal neovascular membranes.
External beam irradiation of subfoveal choroidal neovascularization complicating age-related macular degeneration: one-year results of a prospective, double-masked, randomized clinical trial.2001
A prospective, randomized, double-masked trial on radiation therapy for neovascular age-related macular degeneration (RAD Study). Radiation Therapy for Age-related Macular Degeneration.
Visual outcomes in the subfoveal radiotherapy study: a randomized controlled trial of teletherapy for age-related macular degeneration.2002
Radiotherapy for subfoveal choroidal neovascularization in age-related macular degeneration: a randomized clinical trial.2002
Proof of concept, randomized, placebo-controlled study of the effect of simvastatin on the course of age-related macular degeneration.2013
Full macular translocation versus photodynamic therapy with verteporfin in the treatment of neovascular age-related macular degeneration: 1-year results of a prospective, controlled, randomised pilot trial (FMT-PDT).2007
Digital retroilluminated photography to analyze posterior capsule opacification in eyes with intraocular lenses.2000
Posterior capsule opacification: comparison of 3 intraocular lenses of different materials and design.2003
Position of anterior capsulorhexis and posterior capsule opacification.2004
Factors influencing the formation of posterior capsular opacities after extracapsular cataract extraction with posterior chamber lens implant.1991
Posterior capsule opacification and neodymium: YAG capsulotomy with heparin-surface-modified intraocular lenses.1998
Posterior capsule opacification after phacoemulsification in patients with postoperative steroidal and nonsteroidal treatment.2004
Influence of three-piece and single-piece designs of two sharp-edge optic hydrophobic acrylic intraocular lenses on the prevention of posterior capsule opacification: a prospective, randomised, long-term clinical trial.2007
Combined phacoemulsification and filtering surgery with the 'no-stitch' technique.
Phacoemulsification versus phacoemulsification with micro-bypass stent implantation in primary open-angle glaucoma: randomized double-masked clinical trial.
Fluorophotometric study of the effect of the glaukos trabecular microbypass stent on aqueous humor dynamics.2010
Combined clear cornea phacoemulsification and trabecular aspiration in the treatment of pseudoexfoliative glaucoma associated with cataract.2000
Intraocular pressure response to combined phacoemulsification and trabeculotomy ab externo versus phacoemulsification alone in primary open-angle glaucoma.
Comparative study of trabecular aspiration vs trabeculectomy in glaucoma triple procedure to treat pseudoexfoliation glaucoma.
Phaco-trabeculectomy in controlled, advanced, open-angle glaucoma and cataract: parallel, randomized clinical study of efficacy and safety.
Randomized evaluation of the trabecular micro-bypass stent with phacoemulsification in patients with glaucoma and cataract.
A prospective study of combined phacoemulsification-trabeculectomy versus conventional phacoemulsification in cataract patients with coexisting open angle glaucoma.
Randomized, controlled study of low-dose 5-fluorouracil in primary trabeculectomy.2000
Fluorouracil Filtering Surgery Study one-year follow-up. The Fluorouracil Filtering Surgery Study Group.1989
Single intraoperative application of 5-Fluorouracil versus placebo in low-risk trabeculectomy surgery: a randomized trial.
Trabeculectomy, phacoemulsification, and posterior chamber lens implantation with and without 5-fluorouracil.1993
Postoperative systemic corticosteroid treatment and Molteno implant surgery: a randomized clinical trial.1999
Ahmed glaucoma valve implant vs trabeculectomy in the surgical treatment of glaucoma: a randomized clinical trial.2000
Long-term follow-up of primary glaucoma surgery with Ahmed glaucoma valve implant versus trabeculectomy.2003
A randomized trial of brimonidine versus timolol in preserving visual function: results from the Low-Pressure Glaucoma Treatment Study.
Individualised patient care as an adjunct to standard care for promoting adherence to ocular hypotensive therapy: an exploratory randomised controlled trial.2012
Adherence with brimonidine in patients with glaucoma aware and not aware of electronic monitoring.2011
Comparison of the double-plate Molteno drainage implant with the Schocket procedure.1992
Needling versus medical treatment in encapsulated blebs. A randomized, prospective study.1997
Amniotic membrane transplantation for repair of leaking glaucoma filtering blebs.2000
Randomized clinical trial of the 350-mm2 versus the 500-mm2 Baerveldt implant: longer term results: is bigger better?1999
Efficacy and safety of adjunctive mitomycin C during Ahmed Glaucoma Valve implantation: a prospective randomized clinical trial.2004
A comparison of postoperative complications from pressure-ridge Molteno implants versus Molteno implants with suture ligation.1997
A randomized study of trabeculectomy and subconjunctival administration of fluorouracil in primary glaucomas.1992
A randomized study of 5-fluorouracil and filtration surgery.1987
5-Fluorouracil after primary combined filtration surgery.1994
The effect of surface area expansion with pericardial membrane (preclude) in Ahmed glaucoma valve implant surgery.2004
Prevention of early postoperative hypotony by partial ligation of silicone tube in Ahmed glaucoma valve implantation.2001
A randomised trial of the effect of intraoperative 5-FU on the outcome of trabeculectomy in east Africa.2001
Trabeculectomy with mitomycin. A comparative study with fluorouracil.1991
5-Fluorouracil and mitomycin C in pseudophakic patients.1995
Augmenting trabeculectomy in glaucoma with subconjunctival mitomycin C versus subconjunctival 5-fluorouracil: a randomized clinical trial.
Trabeculectomy with intraoperative 5-fluorouracil vs mitomycin C.1997
Trabeculectomy with intraoperative mitomycin C versus 5-fluorouracil. Prospective randomized clinical trial.2000
The role of antimetabolites in filtration surgery for neovascular glaucoma: intermediate-term follow-up.2007
Deep sclerectomy versus punch trabeculectomy: effect of low-dosage mitomycin C.2005
Nonpenetrating deep sclerectomy versus trabeculectomy in bilateral primary open-angle glaucoma.2000
A comparison of the intraocular pressure-lowering effect and safety of viscocanalostomy and trabeculectomy with mitomycin C in bilateral open-angle glaucoma.2003
Nonpenetrating deep sclerectomy with reticulated hyaluronic acid implant versus punch trabeculectomy: a prospective clinical trial.2008
Primary viscocanalostomy versus trabeculectomy for primary open-angle glaucoma: three-year prospective randomized clinical trial.2004
Effect of a YAG laser iridotomy on intraocular pressure in pigment dispersion syndrome.
YAG laser peripheral iridotomy for the prevention of pigment dispersion glaucoma a prospective, randomized, controlled trial.
Impact of a health communication intervention to improve glaucoma treatment adherence. Results of the interactive study to increase glaucoma adherence to treatment trial.2012
Dorzolamide versus pilocarpine as adjunctive therapies to timolol: a comparison of patient preference and impact on daily life.1996
The influence of health literacy level on an educational intervention to improve glaucoma medication adherence.2012
Comparison of the latanoprost 0.005%/timolol 0.5% + brinzolamide 1% versus dorzolamide 1%/timolol 0.5% + latanoprost 0.005%: a 12-week, randomized open-label trial.
Improving medication compliance: a randomised clinical trial.1979
Comparison of latanoprost monotherapy and combined therapy of 0.5% timolol and 1% dorzolamide in chronic primary angle-closure glaucoma (CACG) in Japanese patients.
Patient preference, efficacy, and compliance with timolol maleate ophthalmic gel-forming solution versus timolol maleate ophthalmic solution in patients with ocular hypertension or open-angle glaucoma.1999
The dorzolamide/timolol combination versus timolol plus pilocarpine: patient preference and impact on daily life. United States Patient Preference Study Group. International Patient Preference Study Group.1999
Longterm effect of topical beta-blockers on intraocular pressure and visual field sensitivity in ocular hypertension and chronic open-angle glaucoma.
Mitomycin C versus 5-fluorouracil in high-risk glaucoma filtering surgery. Extended follow-up.1995
A comparison of the effects of betaxolol, timolol, and pilocarpine on visual function in patients with open-angle glaucoma.1998
Results of the European Glaucoma Prevention Study.2005
Influence of carteolol and timolol on IOP an visual fields in glaucoma: a multi-center, double-masked, prospective study.-- Not Found --
Long-term effects of timolol therapy in ocular hypertension: a double-masked, randomised trial.2000
Longterm visual field follow-up of glaucoma patients treated with beta-blockers.1994
Results of the betaxolol versus placebo treatment trial in ocular hypertension.2003
Timolol treatment prevents or delays glaucomatous visual field loss in individuals with ocular hypertension: a five-year, randomized, double-masked, clinical trial.1989
Argon laser trabeculoplasty in primary open-angle glaucoma--results in black Jamaican population.1988
Peripheral anterior synechiae formation after trabeculoplasty.1988
Laser trabeculoplasty as supplementary treatment for primary open angle glaucoma.1987
Twelve-month results of an ongoing randomized trial comparing brimonidine tartrate 0.2% and timolol 0.5% given twice daily in patients with glaucoma or ocular hypertension. Brimonidine Study Group 2.1998
The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma.2002
A 1-year study of brimonidine twice daily in glaucoma and ocular hypertension. A controlled, randomized, multicenter clinical trial. Chronic Brimonidine Study Group.
Ocular hypertension: correlation of anterior chamber angle width and risk of progression to glaucoma.1992
A 7 year prospective comparative study of three topical beta blockers in the management of primary open angle glaucoma.2001
Comparison of the effects of brimonidine 0.2% and timolol 0.5% on retinal nerve fiber layer thickness in ocular hypertensive patients: a prospective, unmasked study.2005
Decrease of optic disc cupping and pallor of ocular hypertensives with timolol therapy.1995
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.2001
Measurement of adherence to brimonidine therapy for glaucoma using electronic monitoring.2011
Early trabeculectomy versus conventional management in primary open angle glaucoma.1988
A comparison between medical and surgical treatment of glaucoma simplex--results of a prospective study.1968
Influence of treatment protocol on the long-term efficacy of argon laser trabeculoplasty.1993
Bronchial reactivity in healthy individuals undergoing long-term topical treatment with beta-blockers.2005
Fornix-based versus limbal-based conjunctival flaps in initial trabeculectomy with postoperative 5-fluorouracil: four-year follow-up findings.
Limbus-based versus Fornix-based conjunctival flap in filtering surgery. A randomized prospective study.
Comparative results of limbal based versus fornix based conjunctival flaps for trabeculectomy.
Two-site phacotrabeculectomy with intraoperative mitomycin-C: fornix- versus limbus-based conjunctival opening in fellow eyes.
Limbus-based vs fornix-based conjunctival flap in combined glaucoma and cataract surgery with adjunctive mitomycin C.
Ranibizumab versus mitomycin C in primary trabeculectomy--a pilot study.2015
Subconjunctival bevacizumab versus mitomycin C adjunctive to trabeculectomy.2012
Role of subconjunctival bevacizumab as an adjuvant to primary trabeculectomy: a prospective randomized comparative 1-year follow-up study.2015
Laser peripheral iridotomy with and without iridoplasty for primary angle-closure glaucoma: 1-year results of a randomized pilot study.2010
The Advanced Glaucoma Intervention Study (AGIS): 11. Risk factors for failure of trabeculectomy and argon laser trabeculoplasty.2002
Diode laser trabeculoplasty versus argon laser trabeculoplasty in the control of primary open angle glaucoma.1999
Diode laser compared with argon laser for trabeculoplasty.1991
Five-year results of a randomized, prospective, clinical trial of diode vs argon laser trabeculoplasty for open-angle glaucoma.1998
Selective laser trabeculoplasty v argon laser trabeculoplasty: a prospective randomised clinical trial.1999
Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial.2002
Low-dose subconjunctival bevacizumab to augment trabeculectomy for glaucoma.2011
Safety and efficacy of using off-label bevacizumab versus mitomycin C to prevent bleb failure in a single-site phacotrabeculectomy by a randomized controlled clinical trial.2012
Intraocular pressure-lowering effect of auricular acupressure in patients with glaucoma: a prospective, single-blinded, randomized controlled trial.2010
Beta radiation as an adjunct to low-risk trabeculectomy.2000
Effect of beta radiation on success of glaucoma drainage surgery in South Africa: randomised controlled trial.2006
Randomized controlled clinical trial of beta irradiation as an adjunct to trabeculectomy in open-angle glaucoma.2002
Low-dose mitomycin C trabeculectomy in patients with advanced glaucoma.1996
A long-term dose-response study of mitomycin in glaucoma filtration surgery.1997
Adjunctive subconjunctival mitomycin C in glaucoma triple procedure.1995
The role of adjunctive mitomycin C in secondary glaucoma triple procedure as compared to primary glaucoma triple procedure.1998
A fluorophotometric study of corneal endothelium after trabeculectomy using different concentrations of Mitomycin-C.1996
Macular degeneration treatment at Clatterbridge Centre for oncology: treatment and preliminary results2000
An evaluation of the effectiveness of a nurse-led glaucoma monitoring clinic2003
Intravitreal injection of bevacizumab before vitrectomy for proliferative diabetic retinopathy.-- Not Found --
Angiotensin-converting enzyme inhibitor treatment for young normotensive diabetic subjects: a two-year trial.1993
Hospitalization and cataract surgery.1981
Impact of preoperative testing on ophthalmologic and systemic outcomes in cataract surgery.-- Not Found --
The effects of three-piece or single-piece acrylic intraocular lens implantation on posterior capsule opacification.2004
Posterior capsular opacification in pseudophakic eyes with a silicone or acrylic intraocular lens.2002
Argon laser trabeculoplasty with standard and long duration.1990
The immediate pressure response to primary laser trabeculoplasty--a comparison of one- and two-stage treatment.1989
Primary argon laser trabeculoplasty vs. pilocarpine. Short-term effects.1992
A comparative clinical trial of mitomycin C and cyclosporin A in trabeculectomy.1996
Low-dosage mitomycin C as an adjunct to trabeculectomy. A prospective controlled study.1997
Levobunolol compared with timolol for the control of elevated intraocular pressure.1986
Long-term effect of ophthalmic beta-adrenoceptor antagonists on intraocular pressure and retinal sensitivity in primary open-angle glaucoma.1992
Comparison of the ocular effects of three beta-blockers: Timolol, carteolol, and betaxolol1996
The effect of capsulorhexis size on development of posterior capsule opacification: small (4.5 to 5.0 mm) versus large (6.0 to 7.0 mm).2003
Static perimetry evaluation of argon green and dye laser treatment for choroidal neovascular membranes1993
Visaline in the treatment of age-related macular degeneration: a pilot study.1995
A pilot randomized controlled study on the effect of laser photocoagulation of confluent soft macular drusen.
Multifocal versus monofocal intraocular lenses. Visual and refractive comparisons.1992
Prospectively randomized trial comparing the pseudoaccommodation of the AMO ARRAY multifocal lens and a monofocal lens.1993
Performance of diffractive multifocal intraocular lenses in extracapsular cataract surgery.1994
A prospective, randomized, double-masked comparison of a zonal-progressive multifocal intraocular lens and a monofocal intraocular lens.1992
Multicenter ophthalmic and nutritional age-related macular degeneration study--part 2: antioxidant intervention and conclusions.1996
Effect of posterior chamber intraocular lens design and surgical placement on postoperative outcome.1992
Silicone versus polymethylmethacrylate intraocular lenses with regard to capsular opacification.1998
Clinical evaluation of posterior capsule opacification in eyes with different small-incision intraocular lenses.2002
Combined phacoemulsification and filtering surgery with the 'no-stitch' technique.
5-Fluorouracil in initial trabeculectomy. A prospective, randomized, multicenter study.1994
Which is better? One or two? A randomized clinical trial of single-plate versus double-plate Molteno implantation for glaucomas in aphakia and pseudophakia.
Aqueous shunts. Molteno versus Schocket.1992
The effect of a medication alarm device on patient compliance with topical pilocarpine.1996
A clinical trial of timolol and epinephrine in the treatment of primary open-angle glaucoma.1988
A long-term clinical trial of timolol therapy versus no treatment in the management of glaucoma suspects.1989
Levobunolol. A four-year study of efficacy and safety in glaucoma treatment. The Levobunolol Study Group.1989
A comparison of treated and untreated glaucoma suspects.1991
Effect of timolol versus pilocarpine on visual field progression in patients with primary open-angle glaucoma.1992
Long-term functional outcome after early surgery compared with laser and medicine in open-angle glaucoma.1994
A randomized study of mitomycin augmentation in combined phacoemulsification and trabeculectomy.1997
A placebo-controlled, double-masked evaluation of mitomycin C in combined glaucoma and cataract procedures.1996
The Glaucoma Laser Trial (GLT). 2. Results of argon laser trabeculoplasty versus topical medicines. The Glaucoma Laser Trial Research Group.1990
Argon laser trabeculoplasty: comparison of bichromatic and monochromatic wavelengths.1984
Argon laser trabeculoplasty or trabeculectomy a prospective randomised block study.1985

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