Surgical interventions for primary congenital glaucoma (2015)

Project Summary Title and Description

Surgical interventions for primary congenital glaucoma (2015)
Background: Primary congenital glaucoma (PCG) manifests within the first few years of a child's life and is not associated with any other systemic or ocular abnormalities. PCG results in considerable morbidity even in developed countries. Several surgical techniques for treating this condition, and lowering the intraocular pressure (IOP) associated with it, have been described. Objectives: To compare the effectiveness and safety of different surgical techniques for PCG.
Authors of Report
Methodology description
Search methods: We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2014, Issue 6), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to June 2014), EMBASE (January 1980 to June 2014), (January 1982 to June 2014), PubMed (January 1946 to June 2014), the metaRegister of Controlled Trials (mRCT) (, (, the WHO International Clinical Trials Registry Platform (ICTRP) ( We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 23 June 2014. Selection criteria: We included all randomized and quasi-randomized trials in which different types of surgical interventions were compared in children under five years of age with PCG. Data collection and analysis :We used standard methodological procedures specified by The Cochrane Collaboration.
Full report available at:; PMID: 25636153 PMCID: PMC4438567 Data retrospectively entered into SRDR for public accessibility.
Funding Source
National Eye Institute, National Institutes of Health, USA (Grant 1 U01 EY020522); National Institute for Health Research (NIHR), UK

Key Questions

1. What are the effects of surgical interventions for primary congenital glaucoma?

Associated Extraction Forms

Downloadable Data Content

  • XLSX Project Data