Lower Limb Prosthesis

Project Summary Title and Description

Lower Limb Prosthesis
SR for AHRQ and CMS on psychometric properties of functional measures in lower limb amputees, heterogeneity of treatment effect of lower limb prostheses and components (LLP), and long term outcomes.
Authors of Report
Methodology description
Standard systematic review, per AHRQ methodology. Literature searches conducted in PubMed, the Cochrane Central Trials Registry and Cochrane Database of Systematic Reviews, EMBASE, and CINAHL/PsycINFO databases through October 30, 2017.
For KQ 1-3, data extraction/results have been uploaded as a pdf, accessible through the downloadable contents section of the published projects area. Additional extraction/results data for KQ 4 have also been uploaded as a pdf.
Funding Source
AHRQ EPC Program

Key Questions

1. KQ 4: In adults who use a lower limb prosthesis, how do ambulatory, functional, and patient-centered outcomes with different prosthetic components vary based on study participant characteristics?
2. KQ 7: At 6 months, 1 year, and 5 years after receipt of a LLP, (accounting for intervening mortality, subsequent surgeries or injuries) what percentage of individuals…? i. Maintain bipedal ambulation ii. Use their prostheses only for transfers iii Use prostheses only indoors iv. Have abandoned their prostheses v. Have major problems with prosthesis
3. KQ 6: What is the level of patient satisfaction with the process of accessing a LLP (including experiences with both providers and payers)?
4. KQ 1-3: KQ 1. What assessment techniques used to measure functional ability of adults with major lower limb amputation have been evaluated in the published literature? KQ 2. What prediction tools used to predict functional outcomes in adults with major lower limb amputation have been evaluated in the published literature? KQ 3. What functional outcome measurement tools used to assess adults who use a LLP have been evaluated in the published literature?
5. KQ 5: How do study participants’ preprescription expectations of ambulation align with their functional outcomes?

Associated Extraction Forms

Associated Studies (each link opens a new tab)

Functional added value of microprocessor-controlled knee joints in daily life performance of Medicare Functional Classification Level-2 amputees.2011
Energy cost of walking in transfemoral amputees: Comparison between Marlo Anatomical Socket and Ischial Containment Socket.2011
Energy expenditure and cardiac response in above-knee amputees while using prostheses with open and locked knee mechanisms.1985
Benefits for Adults with Transfemoral Amputations and Peripheral Artery Disease Using Microprocessor Compared with Nonmicroprocessor Prosthetic Knees.2015
Comparison of nonmicroprocessor knee mechanism versus C-Leg on Prosthesis Evaluation Questionnaire, stumbles, falls, walking tests, stair descent, and knee preference.2008
Differences in function and safety between Medicare Functional Classification Level-2 and -3 transfemoral amputees and influence of prosthetic knee joint control.2009
Analysis of clinically important factors on the performance of advanced hydraulic, microprocessor-controlled exo-prosthetic knee joints based on 899 trial fittings.2016
Impact on the biomechanics of overground gait of using an 'Echelon' hydraulic ankle-foot device in unilateral trans-tibial and trans-femoral amputees.2014
Functional Stability of Transfemoral Amputee Gait Using the 3R80 and Total Knee 2000 Prosthetic Knee Units2009
Use and satisfaction with prosthetic limb devices and related services.2004
Subjective benefits of energy storing prostheses.1994
Prosthetic use and functional and social outcome following major lower limb amputation.1990
Enabling factors related to prosthetic use by people with transtibial and transfemoral amputation.
The effect of a shock-absorbing pylon on the gait of persons with unilateral transtibial amputation.2003
Satisfaction rates amongst elderly amputees provided with a static prosthetic foot.2011
Mobility outcome following unilateral lower limb amputation.2003
Locomotor Performance During Rehabilitation of People With Lower Limb Amputation and Prosthetic Nonuse 12 Months After Discharge.2016
Correlations with patients' perspectives of the result of lower-extremity amputation.2000
Influencing factors of outcome after lower-limb amputation: a five-year review in a plastic surgical department.2008
The Geriatric Amputee Post-Discharge from Successful Rehabilitation1994

Downloadable Data Content

  • XLSX Project Data