Systematic Review on the Use of Cryotherapy Versus other Treatments for Basal Cell Carcinoma

Project Summary Title and Description

Title
Systematic Review on the Use of Cryotherapy Versus other Treatments for Basal Cell Carcinoma
Description
Our objective is to determine the efficacy and adverse events profile of cryotherapy for the treatment of basal cell carcinoma compared to other therapeutic options or non intervention.
Attribution
N/A
Authors of Report
N/A
Methodology description
We systematically searched PubMed, OVID, the Cochrane Library, EMBASE, CINHAL, and CANCERLIT databases with the following search terms: “cryotherapy”, AND “basal cell carcinoma”, OR “cryosurgery” OR “cryoablation” uup to November 2016. Two independent reviewers screened the search results and extracted the databased on the inclusion criteria, while a third reviewer resolved any disagreement. The study endpoints included recurrence of basal cell carcinoma, cosmetic outcome, and healing time. The study quality was assessed using the Jadad scale.
PROSPERO
CRD42016049157
DOI
10.26300/81bq-xw45
Notes
Included in this project, we uploaded the following files: 1- Flow diagram of study selection for systematic review 2- Clinical studies of cryotherapy for the treatment of basal cell carcinoma Note: The data was entered into this project retrospectively.
Funding Source
No funding/sponsor was involved in the preparation of this manuscript.

Key Questions

1. What is the efficacy of cryotherapy for the treatment of basal cell carcinoma compared to other therapeutic options or non intervention?
2. What is the adverse events profile of cryotherapy for the treatment of basal cell carcinoma compared to other therapeutic options or non intervention?

Associated Extraction Forms

Associated Studies (each link opens a new tab)

TitleAuthorsYear
Consensus for nonmelanoma skin cancer treatment: basal cell carcinoma, including a cost analysis of treatment methods.2015
Interventions for basal cell carcinoma of the skin.2007
Treatment of basal cell carcinoma with curettage alone.2006
Basal cell carcinoma: treatment options and prognosis, a scientific approach to a common malignancy.2002
Prospective trial of curettage and cryosurgery in the management of non-facial, superficial, and minimally invasive basal and squamous cell carcinoma.2011
The role of radiation therapy in the management of skin cancers.2011
Nonmelanoma skin cancer.2012
Do lasers or topicals really work for nonmelanoma skin cancers?2011
Topical imiquimod or fluorouracil therapy for basal and squamous cell carcinoma: a systematic review.2009
Topical and intralesional treatment of nonmelanoma skin cancer: efficacy and cost comparisons.2013
Treatment of nodular basal cell carcinoma with cryotherapy and reduced protocol of imiquimod.2012
Cryoimmunotherapy: superficial basal cell cancer and squamous cell carcinoma in situ treated with liquid nitrogen followed by imiquimod.2011
Vismodegib: First-in-Class Hedgehog Pathway Inhibitor for Metastatic or Locally Advanced Basal Cell Carcinoma.-- Not Found --
Assessing the quality of reports of randomized clinical trials: is blinding necessary?1996
The Cochrane Collaboration's tool for assessing risk of bias in randomised trials.
Treatment of basal-cell carcinoma: comparison of radiotherapy and cryotherapy.1986
Photodynamic therapy vs. cryosurgery of basal cell carcinomas: results of a phase III clinical trial.2001
Blood perfusion studies on basal cell carcinomas in conjunction with photodynamic therapy and cryotherapy employing laser-Doppler perfusion imaging.-- Not Found --
Photodynamic therapy of non-melanoma malignant tumours of the skin using topical delta-amino levulinic acid sensitization and laser irradiation.1994
Topical methyl aminolaevulinate photodynamic therapy versus cryotherapy for superficial basal cell carcinoma: a 5 year randomized trial.-- Not Found --
Cosmetic results of cryosurgery versus surgical excision for primary uncomplicated basal cell carcinomas of the head and neck.2000
Surgical excision versus curettage plus cryosurgery in the treatment of basal cell carcinoma.2007
Allocation concealment in randomised trials: defending against deciphering.2002
Randomisation.1991
Statistics review 12: survival analysis.2004
The treatment of basal cell carcinoma patients by dermatologists in Netherland.1998
Mohs surgery is the treatment of choice for recurrent (previously treated) basal cell carcinoma.1989
Interventions for basal cell carcinoma of the skin: systematic review.2004
Guidelines for the management of basal cell carcinoma. British Association of Dermatologists.1999
Light fractionation significantly improves the response of superficial basal cell carcinoma to aminolaevulinic acid photodynamic therapy: five-year follow-up of a randomized, prospective trial.2012
Overall treatment success after treatment of primary superficial basal cell carcinoma: a systematic review and meta-analysis of randomized and nonrandomized trials.2012
Current modalities and new advances in the treatment of basal cell carcinoma.2006
Non-melanoma skin cancer.2010
Guidelines for topical photodynamic therapy: update.2008
Basal cell carcinoma: an evidence-based treatment update.2014
Basal Cell Skin Cancer, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology.2016
Five-year results of curettage-cryosurgery for 100 consecutive auricular non-melanoma skin cancers.2002
Facial basal cell carcinoma.

Downloadable Data Content

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