Masks for Prevention of COVID-19 in Community and Healthcare Settings: A Living Rapid Review

Project Summary Title and Description

Masks for Prevention of COVID-19 in Community and Healthcare Settings: A Living Rapid Review
To address the comparative effectiveness of various types of face masks in healthcare workers and in the community and to address the effectiveness and safety of mask reuse. Surveillance Report, July 20, 2020 Version 2, June 24, 2020 Version 1, June 18, 2020
Authors of Report
Methodology description
We initially searched PubMed MEDLINE and Elsevier Embase (from 2003 through April 14, 2020) and conducted ongoing search updates to identify new studies (surveillance). The WHO Database of Publications on Coronavirus Disease, and the medRxiv preprint server were also searched initially. Reference lists of systematic reviews and included studies were reviewed for additional studies.
DOI: Attached documents are: Appendix B1. Randomized Controlled Trials of Masks 6.18.20 Appendix B2. Observational Studies of Masks in the Community 7.20.20 Appendix B3. Observational Studies of Masks in Healthcare Settings 6.24.20
Funding Source
Agency for Healthcare Research and Quality. Prepared by the Pacific Northwest Evidence-based Practice Center, Oregon Health & Science University. AHRQ Publication No. 20-EHC016.

Key Questions

1. What is the effectiveness of respirators (e.g. N95) vs. facemasks (surgical) vs. cloth masks for prevention of COVID-19 in addition to standard precautions (gowns + gloves + handwashing)? a. In community settings b. In healthcare settings b1. In high-risk healthcare settings (e.g. ICU, ER) b2. In healthcare settings with close contact but unknown risk (e.g. primary care, other settings)
2. What is the evidence for extended or re-use of N95 respirators for prevention of COVID-19?

Associated Extraction Forms


Associated Studies (each link opens a new tab)

Title Authors Year
Mask use, hand hygiene, and seasonal influenza-like illness among young adults: a randomized intervention trial. 2010
Facemasks, hand hygiene, and influenza among young adults: a randomized intervention trial.
Risk Factors for Middle East Respiratory Syndrome Coronavirus Infection among Healthcare Personnel. 2016
Pilot Randomised Controlled Trial to Test Effectiveness of Facemasks in Preventing Influenza-like Illness Transmission among Australian Hajj Pilgrims in 2011. 2014
Surgical mask to prevent influenza transmission in households: a cluster randomized trial. 2010
Intubation of SARS patients: infection and perspectives of healthcare workers. 2006
Which preventive measures might protect health care workers from SARS? 2009
Compliance with the Use of Medical and Cloth Masks Among Healthcare Workers in Vietnam. 2016
Facemasks and hand hygiene to prevent influenza transmission in households: a cluster randomized trial. 2009
Preliminary findings of a randomized trial of non-pharmaceutical interventions to prevent influenza transmission in households. 2008
Impact of non-pharmaceutical interventions on URIs and influenza in crowded, urban households. -- Not Found --
Probable secondary infections in households of SARS patients in Hong Kong.
SARS transmission among hospital workers in Hong Kong.
Surgical mask vs N95 respirator for preventing influenza among health care workers: a randomized trial. 2009
SARS among critical care nurses, Toronto.
A case-control study on the risk factors of severe acute respiratory syndromes among health care workers. 2004
Face mask use and control of respiratory virus transmission in households. 2009
A cluster randomised trial of cloth masks compared with medical masks in healthcare workers. 2015
A cluster randomized clinical trial comparing fit-tested and non-fit-tested N95 respirators to medical masks to prevent respiratory virus infection in health care workers. 2011
A randomized clinical trial of three options for N95 respirators and medical masks in health workers. 2013
Cluster randomised controlled trial to examine medical mask use as source control for people with respiratory illness. 2016
Rapid awareness and transmission of severe acute respiratory syndrome in Hanoi French Hospital, Vietnam. 2005
Risk factors for SARS infection within hospitals in Hanoi, Vietnam. 2008
Investigation of the influencing factors on severe acute respiratory syndrome among health care workers. 2006
Risk factors for SARS transmission from patients requiring intubation: a multicentre investigation in Toronto, Canada. 2010
N95 Respirators vs Medical Masks for Preventing Influenza Among Health Care Personnel: A Randomized Clinical Trial. 2019
Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS). 2003
Findings from a household randomized controlled trial of hand washing and face masks to reduce influenza transmission in Bangkok, Thailand. 2011
The role of facemasks and hand hygiene in the prevention of influenza transmission in households: results from a cluster randomised trial; Berlin, Germany, 2009-2011.
Factors associated with transmission of severe acute respiratory syndrome among health-care workers in Singapore. 2004
SARS transmission in Vietnam outside of the health-care setting. 2007
Asymptomatic SARS coronavirus infection among healthcare workers, Singapore. 2005
Risk factors for SARS among persons without known contact with SARS patients, Beijing, China. 2004
Effectiveness of personal protective measures in prevention of nosocomial transmission of severe acute respiratory syndrome. 2004
Facemask versus no facemask in preventing viral respiratory infections during Hajj: a cluster randomised open label trial 2019
Risk factors for SARS infection among hospital healthcare workers in Beijing: a case control study. Tropical Medicine & International Health 2009
Association between 2019-nCoV transmission and N95 respirator use. Journal of Hospital Infection
Transmission of COVID-19 to Health Care Personnel During Exposures to a Hospitalized Patient - Solano County, California, February 2020. 2020
Illness in intensive care staff after brief exposure to severe acute respiratory syndrome. 2003
Reduction of secondary transmission of SARS-CoV-2 in households by face mask use, disinfection and social distancing: a cohort study in Beijing, China. 2020

Downloadable Data Content

  • XLSX Project Data