Extraction form for project: Interventional Treatments for Acute and Chronic Pain: Systematic Review

Design Details

1. Trial Intervention
Input which intervention is being studied
Single Choice
Vertebroplasty
Kyphoplasty
Cooled radiofrequency ablation
Pulsed radiofrequency ablation
Platelet-rich plasma
Intradiscal stem cell
Intradiscal methylene blue
Intradiscal ozone
Sphenopalatine block
Occipital nerve stimulation
Piriformis injection
Peripheral nerve stimulation
2. Trial Name
3. Setting
Country
4. Study Design
5. Mean Age (Years)
Input the mean age for the entire sample
6. Percent Female
Input the whole number here for the entire study sample - no need to add %
7. Number Randomized
8. Pain Duration Measure (Mean, Median)
Single Choice
Mean
Median
ND
9. Pain Duration (Weeks)
10. Duration of Followup (Months)

Arm Details

N/A

Sample Characteristics

N/A

Outcome Details

N/A

Risk of Bias Assessment

1. What kind of study is this?
Single Choice
RCT
2. Randomization adequate?
Single Choice
Yes
No
Unclear
3. Allocation concealment adequate?
Single Choice
Yes
No
Unclear
4. Groups similar at baseline?
Single Choice
Yes
No
Unclear
No (pai
No (pain)
No (ODI)
No (pain, EQ-5D)
No (% female)
5. Outcome assessors masked?
Single Choice
Yes
No
Unclear
No (except for safety)
6. Care provider masked?
Single Choice
Yes
No
Unclear
7. Patient masked?
Single Choice
Yes
No
Unclear
8. Acceptable levels of overall attrition and between-group differences in attrition?
9. Intention-to-Treat (ITT) analysis?
Single Choice
Yes
No
Unclear
No (at 3 months and beyond, due to high crossover)
10. Avoidance of selective outcomes reporting
Single Choice
Yes
No
Unclear
11. Quality rating
Single Choice
Good
Fair
Poor

Suggested Arms

NameDescription
Interventions and ComparisonsAdd labels for the interventions and comparisons (typically Intervention A (treatment) and Intervention B (control)).
Total All Arms combined

Please see downloadable data for more

Suggested Outcomes

TypeDomainSpecific measurement (i.e., tool/definition/specific outcome)
CategoricalFunctionRDQ improvement >=30%
CategoricalHarms
CategoricalPainNRS <4 (0 to 10 scale)
CategoricalPainPain improvement >=30%
CategoricalPainPerceived pain moderately or a great deal better
CategoricalPainSuccessful outcome defined as ≥50% improvement in pain, positive Global Perceived Effect, and ≥10-point improvement in ODI or ≥4 point improvement in ODI and >20% reduction in opioid use or complete cessation of nonopioid analgesic
CategoricalPainVertebral pain <4 on 0 to 10 VAS
ContinuousFunction
ContinuousFunctionFRI 0 to 100, mean difference (95% CI)
ContinuousFunctionModified RDQ (mean [SD], 0 to 23 scale)
ContinuousFunctionModified RDQ (mean change from baseline [SD], 0 to 23 scale)
ContinuousFunctionODI (mean [SD], 0 to 100 scale)
ContinuousFunctionODI (mean change from baseline [SD], 0 to 100 scale)
ContinuousFunctionODI LSM (95% CI)
ContinuousFunctionRDQ (mean [SD], 0 to 24 scale)
ContinuousFunctionRDQ (mean change from baseline [SD], 0 to 24 scale)
ContinuousFunction (Change)
ContinuousPain
ContinuousPainDallas Pain Questionnaire, anxiety and depression (mean [SD], 0 to 100 scale)
ContinuousPainDallas Pain Questionnaire, daily activities (mean [SD], 0 to 100 scale)
ContinuousPainNRS 0 to 10 worst pain, mean difference (95% CI)
ContinuousPainOverall pain (mean change from baseline [SD], 0 to 10 VAS)
ContinuousPainPain (mean [SD] improvement from baseline, 0 to 10 VAS)
ContinuousPainPain at rest (mean [SD], 0 to 10 VAS)
ContinuousPainPain intensity (mean [SD], 0 to 10 NRS)
ContinuousPainPain intensity (mean [SD], 0 to 10 VAS)
ContinuousPainPain intensity (mean [SD], 0 to 100 VAS converted to 0 to 10 scale)
ContinuousPainPain intensity (mean change from baseline [SD], 0 to 10 NRS)
ContinuousPainVAS LSM (95% CI)
ContinuousPain (Change)

Please see downloadable data for more