- Title
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Interventions for Breathlessness in Patients with Advanced Cancer
- Description
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To assess benefits and harms of non-pharmacological and pharmacological interventions for breathlessness in adults with advanced cancer.
- Attribution
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N/A
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Authors of Report
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N/A
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Methodology description
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We included randomized controlled trials (RCTs) and observational studies with a comparison group evaluating benefits and/or harms and cohort studies reporting harms. Two reviewers independently screened search results, serially abstracted data, assessed risk of bias and graded strength of evidence (SOE) for key outcomes: breathlessness, anxiety, health-related quality of life (HRQOL) and exercise capacity. We performed meta-analyses when possible and calculated standardized mean differences (SMDs).
- PROSPERO
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N/A
- DOI
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N/A
- Notes
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The published report may be found at: https://effectivehealthcare.ahrq.gov/sites/default/files/pdf/dyspnea-advanced-cancer-report.pdf
Data was uploaded retrospectively to SRDR. Each Key Question's data file contains information on study and patient characteristics, intervention information, and detailed outcomes data for both categorical and continuous outcomes.
Data files used to synthesis the report are found at:
https://srdr.s3.amazonaws.com/uploads/10-29-2021/Breathlessness_compiled+data_KQ1_KQ4.xlsx
https://srdr.s3.amazonaws.com/uploads/10-29-2021/Breathlessness_compiled+data_KQ2_KQ4.xlsx
https://srdr.s3.amazonaws.com/uploads/10-29-2021/Breathlessness_compiled+data_KQ3_KQ4.xlsx
- Funding Source
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N/A