Extraction form for project: Management of Primary Headache During Pregnancy

Arms

Arm NameArm Description
Triptans: Any
Triptans: Any (before pregnancy only)
Triptans: None (before or during pregnancy)

Arm Details

1. Provide a BRIEF DESCRIPTION of the intervention.
Skip if the rest of the questions answer this, e.g., for a specific drug name. If multiple pharm/non-pharm interventions, enter then just list them.
Triptans: Any
Triptans: Any (before pregnancy only)
Triptans: None (before or during pregnancy)
2. What was the DOSE of the drug?
Include amount (number) and unit, with a space between them. Skip if not applicable. Enter "NR" if not reported.
Triptans: Any
Triptans: Any (before pregnancy only)
Triptans: None (before or during pregnancy)
3. What was the ROUTE of the drug?
If there was a change in route mid-course, enter all applicable routes and also explain using the "Other" option. Skip if not applicable.
Triptans: Any
Triptans: Any (before pregnancy only)
Triptans: None (before or during pregnancy)
4. What was the FREQUENCY of the intervention?
Enter number per time period, e.g., 3/day. For single dose/time interventions, enter "Once". Enter "NR" if not reported.
Triptans: Any
Triptans: Any (before pregnancy only)
Triptans: None (before or during pregnancy)
5. What was the DURATION of the intervention?
Include number and unit, with a space between them.
Triptans: Any
Triptans: Any (before pregnancy only)
Triptans: None (before or during pregnancy)
6. Do you have any NOTES regarding the arms in this study?
Leave blank if you don't.
Triptans: Any
Triptans: Any (before pregnancy only)
Triptans: None (before or during pregnancy)

Outcomes

TypeDomainSpecific MeasurementPopulationsTimepoints
CategoricalAdverse events - Fetal/Infant - Congenital anomalies or other newborn abnormalitiesAny
  • All Participants
  • 1st trimester
  • 2nd and/or 3rd trimester
  • Delivery (N/A)
CategoricalAdverse events - Fetal/Infant - Congenital anomalies or other newborn abnormalitiesMajor
  • All Participants
  • 1st trimester
  • 2nd and/or 3rd trimester
  • Delivery (N/A)
CategoricalAdverse events - Fetal/Infant - Death, spontaneous abortion, stillbirth, infant deathStillbirth
  • All Participants
  • 1st trimester
  • 2nd and/or 3rd trimester
  • Delivery (N/A)
CategoricalAdverse events - Fetal/Infant - Death, spontaneous abortion, stillbirth, infant deathPerinatal death
  • All Participants
  • 1st trimester
  • 2nd and/or 3rd trimester
  • Delivery (N/A)
CategoricalAdverse events - Fetal/Infant - Death, spontaneous abortion, stillbirth, infant deathInfant death
  • All Participants
  • 1st trimester
  • 2nd and/or 3rd trimester
  • 1 (years)
CategoricalAdverse events - Fetal/Infant - Low birth weight<2500 g
  • All Participants
  • 1st trimester
  • 2nd and/or 3rd trimester
  • Delivery (N/A)
CategoricalAdverse events - Fetal/Infant - Preterm birthGestational age <37 weeks
  • All Participants
  • 1st trimester
  • 2nd and/or 3rd trimester
  • Delivery (N/A)
CategoricalAdverse events - Fetal/Infant - Perinatal complicationsApgar score <7
  • All Participants
  • 1st trimester
  • 2nd and/or 3rd trimester
  • 1 (minutes)
  • 5 (minutes)
CategoricalAdverse events - Maternal - OtherPostpartum hemorrhage >500 ml
  • All Participants
  • 1st trimester
  • 2nd and/or 3rd trimester
  • Delivery (N/A)
CategoricalAdverse events - Fetal/Infant - Behavioral/SocialClinically significant externalizing behavior problems on the Child Behavior Checklist (CBCL)
  • All Participants
  • 1st trimester
  • 2nd and/or 3rd trimester
  • 3 (years)
  • 5 (years)
CategoricalAdverse events - Fetal/Infant - Behavioral/SocialClinically significant internalizing behavior problems on the Child Behavior Checklist (CBCL)
  • All Participants
  • 1st trimester
  • 2nd and/or 3rd trimester
  • 3 (years)
  • 5 (years)
CategoricalAdverse events - Fetal/Infant - Behavioral/SocialExternalizing problems - At or above a Z-score of 1.5 on the Child Behavior Checklist (CBCL)
  • All Participants
  • 1.5 (years)
  • 3 (years)
CategoricalAdverse events - Fetal/Infant - Behavioral/SocialEmotionality - At or above a Z-score of 1.5 on the Child Behavior Checklist (CBCL)
  • All Participants
  • 1.5 (years)
  • 3 (years)
CategoricalAdverse events - Fetal/Infant - Behavioral/SocialActivity - At or above a Z-score of 1.5 on the Emotionality, Activity, and Shyness Temperament Questionnaire
  • All Participants
  • 1.5 (years)
  • 3 (years)
CategoricalAdverse events - Fetal/Infant - Behavioral/SocialShyness - At or above a Z-score of 1.5 on the Emotionality, Activity, and Shyness Temperament Questionnaire
  • All Participants
  • 1.5 (years)
  • 3 (years)
CategoricalAdverse events - Fetal/Infant - Behavioral/SocialSociability - At or above a Z-score of 1.5 on the Emotionality, Activity, and Shyness Temperament Questionnaire
  • All Participants
  • 1.5 (years)
  • 3 (years)
CategoricalAdverse events - Fetal/Infant - Behavioral/SocialInternalizing symptoms - At or above a Z-score of 1.5 on the Child Behavior Checklist (CBCL)
  • All Participants
  • 3 (years)
  • 1.5 (years)
CategoricalAdverse events - Fetal/Infant - NeurodevelopmentalGross motor development - At or above a Z-score of 1.5 on the Ages and Stages Questionnaire (ASQ)
  • All Participants
  • 1.5 (years)
  • 3 (years)
CategoricalAdverse events - Fetal/Infant - NeurodevelopmentalFine motor development - At or above a Z-score of 1.5 on the Ages and Stages Questionnaire (ASQ)
  • All Participants
  • 1.5 (years)
  • 3 (years)
CategoricalAdverse events - Fetal/Infant - Behavioral/SocialCommunication development - At or above a Z-score of 1.5 on the Ages and Stages Questionnaire (ASQ)
  • All Participants
  • 1.5 (years)
  • 3 (years)
ContinuousAdverse events - Fetal/Infant - Behavioral/SocialEmotionality on the Emotionality, Activity, and Shyness Temperament Questionnaire
  • All Participants
  • 5 (years)
ContinuousAdverse events - Fetal/Infant - Behavioral/SocialActivity on the Emotionality, Activity, and Shyness Temperament Questionnaire
  • All Participants
  • 5 (years)
ContinuousAdverse events - Fetal/Infant - Behavioral/SocialShyness on the Emotionality, Activity, and Shyness Temperament Questionnaire
  • All Participants
  • 5 (years)
ContinuousAdverse events - Fetal/Infant - Behavioral/SocialSociability on the Emotionality, Activity, and Shyness Temperament Questionnaire
  • All Participants
  • 5 (years)
CategoricalAdverse events - Fetal/Infant - Behavioral/SocialClinically significant communication problems on the Ages and Stages Questionnaire (ASQ)
  • All Participants
  • 5 (years)

Design

1. Which KEY QUESTION (KQ) does this study address?
Select all that apply.
2. What is the STUDY DESIGN?
3. What was the ANALYTIC METHOD used to control for differences between study groups?
Select all that apply.
4. What was the DIRECTIONALITY of the study?
5. Does the study have a CLINICALTRIALS.GOV IDENTIFICATION NUMBER?
6. In what COUNTRY was the study done?
Select all that apply.
7. What was the FUNDING SOURCE of the study?
Select all that apply.
8. Does the study have a NAME or ACRONYM?
9. What were the START and END YEARS of the study?
Years (not months). If either is not reported, enter "NR" in the appropriate cell(s).
Start yearEnd year
Years
10. What were the study INCLUSION criteria?
Keep succinct. Use common abbreviations. Omit criteria of minor relevance (e.g., language, consent). Enter "NR" if not reported.
11. What were the study EXCLUSION criteria?
Keep succinct. Use common abbreviations. Omit criteria of minor relevance (e.g., language, consent). Enter "NR" if not reported.
12. Do you have any NOTES regarding the design or any overall aspects of this study?
Leave blank if you don't.
13. How many DATABASES did the authors search?
14. What was the YEAR of the last search?
15. How many STUDIES were included in the review?
16. What INTERVENTIONS were addressed?
ClassIntervention
Intervention 1
Intervention 2
Intervention 3
Intervention 4
Intervention 5
17. Were MATERNAL adverse events reported?
18. Were FETAL/CHILD adverse events reported?
19. AMSTAR Item 1 - Did the authors specify the research questions and inclusion criteria for the SR?
20. AMSTAR Item 4 - Did the SR authors use a comprehensive literature search strategy?
21. AMSTAR Item 5 - Did the SR authors perform study selection in duplicate?
22. AMSTAR Item 6 - Did the SR authors perform data extraction in duplicate, either independently or through verification?
23. AMSTAR Item 8 - Did the SR authors describe the included studies in adequate detail?
24. AMSTAR Item 9 - Did the SR authors use a satisfactory technique for assessing the risk of bias in individual studies that were included in the SR?
25. AMSTAR Item 12 - Did the SR authors assess the potential impact of risk of bias in individual studies on the summary results, interpretation, discussion?
26. AMSTAR Item 11 - If meta-analysis (MA) was performed did the SR authors use appropriate methods for statistical combination of results?
27. AMSTAR Item 14 - Did the SR authors provide a satisfactory explanation for, and discussion of, any heterogeneity observed in the results of the SR?
28. AMSTAR Item 16 - Did the SR authors report the lack of significant potential of conflict of interest (COI) regarding conducting the SR?
29. What was the OVERALL QUALITY OF THE SYSTEMATIC REVIEW
30. MATERNAL Adverse Events - ANTEPARTUM
N StudiesEffect MeasureEffect Size95% CI LL95% CI ULConclusion
Adverse effect, Any
Antepartum hemorrhage
Eclampsia
Hospitalization during pregnancy
Placental abruption
Pregnancy-induced hypertension
Thrombosis
31. MATERNAL Adverse Events - DELIVERY
N StudiesEffect MeasureEffect Size95% CI LL95% CI ULConclusion
Cesarean section
Induction of labor
Induction of labor or cesarean section
Length of labor
32. MATERNAL Adverse Events - POSTPARTUM
N StudiesEffect MeasureEffect Size95% CI LL95% CI ULConclusion
Postpartum diastolic blood pressure
Postpartum hemorrhage
Postpartum hypertension
Postpartum mean arterial pressure
Postpartum systolic blood pressure
33. MATERNAL Adverse Events - TIMING NOT REPORTED
N StudiesEffect MeasureEffect Size95% CI LL95% CI ULConclusion
Adverse effects, Any
Absent or reduced tendon reflexes
Blurred vision
Cardiac arrest
Death
Diastolic blood pressure
Discontinuation due to adverse effects
Dizziness
Drowsiness or confusion
Flushing and/or warmth
Gastrointestinal symptoms
Headache
Hospitalizations
Hypotension
Itching and/or tingling
Muscle weakness
Nausea and/or vomiting
Pulmonary edema
Respiratory arrest
Respiratory depression/other respiratory problems
Slurred speech
Sweating
Systolic blood pressure
Tachycardia
Thirst or mouth dryness
34. FETAL/CHILD Adverse Events - IN UTERO
N StudiesEffect MeasureEffect Size95% CI LL95% CI ULConclusion
Fetal death or spontaneous abortion
Fetal growth restriction
Fetal intracranial hemorrhage
Fetal or neonatal death, including spontaneous abortion
Spontaneous abortion
Spontaneous abortion or stillbirth
35. FETAL/CHILD Adverse Events - PERINATAL
N StudiesEffect MeasureEffect Size95% CI LL95% CI ULConclusion
Birth weight
Gestational age at birth
Large for gestational age
Low birth weight
Perinatal death
Preterm birth
Small for gestational age
Stillbirth
36. FETAL/CHILD Adverse Events - NEONATAL
N StudiesEffect MeasureEffect Size95% CI LL95% CI ULConclusion
Adverse effects, Any
Bronchopulmonary dysplasia
IGNORE
Congenital anomalies, All or major
Congenital anomalies, Any
Congenital anomalies, Atrial septum defect
Congenital anomalies, Cardiovascular
Congenital anomalies, Cleft lip
Congenital anomalies, Cleft lip or palate
Congenital anomalies, Cleft palate
Congenital anomalies, Club foot
Congenital anomalies, Diaphragmatic hernia
Congenital anomalies, Genitourinary
Congenital anomalies, Hypoplastic left heart
Congenital anomalies, Hypospadias
Congenital anomalies, Major
Congenital anomalies, Minor
Congenital anomalies, Neural tube defects
Congenital anomalies, Oral cleft
Congenital anomalies, Orofacial clefts
Congenital anomalies, Respiratory system anomalies
Congenital anomalies, Severe hypospadias
Congenital anomalies, Skeletal or limb defects
Congenital anomalies, Ventricular septum defect
Hospitalization
Inguinal hernia
Intraventricular hemorrhage
Intraventricular hemorrhage: Grade III-IV
Necrotizing enterocolitis
Neonatal bradycardia
Neonatal convulsions
Neonatal hypoglycemia
Neonatal jaundice
Neonatal mortality
Neonatal pulmonary edema
Neonatal respiratory distress
Neonatal withdrawal symptoms
NICU admission
Other neonatal bleed
Patent ductos arteriosus
Periventricular leukomalacia
Respiratory distress syndrome
Sepsis
Undescended testes
37. FETAL/CHILD Adverse Events - CHILD
N StudiesEffect MeasureEffect Size95% CI LL95% CI ULConclusion
Attention deficit hyperactivity disorder
Autism spectrum disorder
Autism/dyspraxia
IGNORE
Behavior problems (at 18 months)
Child hospitalization (at 12 months)
Child hospitalization (at 18 months)
Cognitive developmental delay
Conduct disorder
Developmental outcomes
Hearing problems
Hyperactivity symptoms
Inability to sit without support at 6 months
Infant death (after discharge)
Language delay
Language problems, Undefined
Malformations (at 18 months)
Motor or speech delays
Poor fine motor function
Poor gross motor function
Poor growth (at 18 months)
Poor language comprehension
Poor language expression
Psychomotor developmental delay
Respiratory problems
Sight problems

Outcome Details

N/A

Baselines

1. What was the SAMPLE SIZE at baseline?
2. What were the RACE/ETHNICITY of the women in the study?
Select and enter data for all that apply. Percentages only (not proportions).
3. What was the AGE DISTRIBUTION of the women in the study? (CONTINUOUS data)
Select and enter data for all that apply. Categorical age data are in the next question.
4. What was the AGE DISTRIBUTION of the women in the study? (CATEGORICAL data)
Define the categories and then report % in each category. Skip question if categorical age data are not reported.
Definition of category%
Youngest category
2nd category
3rd category
4th category
5th category
6th category
7th category
5. In what PHASE were the women in the study?
Select and enter data for all that apply. Percentages only (not proportions).
6. What was the GESTATIONAL AGE DISTRIBUTION of the women in the study? (CONTINUOUS data)
Select and enter data for all that apply.
7. What was the UNIT for the gestational age you answered in the previous question?
Leave blank if gestational age was not reported.
8. What was the GRAVIDITY DISTRIBUTION of the women in the study? (CONTINUOUS data)
Gravidity refers to the total number of times that a woman has been pregnant, irrespective of the outcome. Select and enter data for all that apply.
9. What was the PARITY DISTRIBUTION of the women in the study? (CONTINUOUS data)
Parity refers to the total number of births that a woman has had after 20 weeks gestation. Select and enter data for all that apply.
10. What were the TYPES of PRIMARY HEADACHE in the women in the study?
Select and enter data for all that apply. Percentages only (not proportions).
11. What percentage of the women in the study had a HISTORY OF PRIMARY HEADACHE?
Select and enter data for all that apply. Percentages only (not proportions).
12. Do you have any NOTES regarding the baseline characteristics in this study?
Skip if you don't.

Results

Categorical


Adverse events - Fetal/Infant - Congenital anomalies or other newborn abnormalities (Any)

All Participants
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1st trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
2nd and/or 3rd trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)

Adverse events - Fetal/Infant - Congenital anomalies or other newborn abnormalities (Major)

All Participants
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1st trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
2nd and/or 3rd trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)

Adverse events - Fetal/Infant - Death, spontaneous abortion, stillbirth, infant death (Stillbirth)

All Participants
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1st trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
2nd and/or 3rd trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)

Adverse events - Fetal/Infant - Death, spontaneous abortion, stillbirth, infant death (Perinatal death)

All Participants
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1st trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
2nd and/or 3rd trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)

Adverse events - Fetal/Infant - Death, spontaneous abortion, stillbirth, infant death (Infant death)

All Participants
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1 (years)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1st trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1 (years)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
2nd and/or 3rd trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1 (years)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)

Adverse events - Fetal/Infant - Low birth weight (<2500 g)

All Participants
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1st trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
2nd and/or 3rd trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)

Adverse events - Fetal/Infant - Preterm birth (Gestational age <37 weeks)

All Participants
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1st trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
2nd and/or 3rd trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)

Adverse events - Fetal/Infant - Perinatal complications (Apgar score <7)

All Participants
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1 (minutes)
N Analyzed
Counts
Percentage
5 (minutes)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1st trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1 (minutes)
N Analyzed
Counts
Percentage
5 (minutes)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
2nd and/or 3rd trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1 (minutes)
N Analyzed
Counts
Percentage
5 (minutes)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)

Adverse events - Maternal - Other (Postpartum hemorrhage >500 ml)

All Participants
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
1st trimester
Descriptive StatisticsBetween Arm Comparisons
Triptans: AnyTriptans: Any (before pregnancy only)Triptans: None (before or during pregnancy)
Delivery (N/A)
N Analyzed
Counts
Percentage
Within Arm ComparisonsNet Comparisons