Extraction form for project: IPMP (Integrated Pain Management Programs)

Design Details

1. What type of program does the study assess (IPMP or CPMP)?
Integrated Pain Management Program (IPMP): Based in, integrated with, coordinated by primary care. Comprehensive Pain Management Program (CPMP): Referral based and separate from primary care.
2. In what country was the study conducted?
List all applicable countries.
3. What study design was used?
Please select the appropriate study design for the study. If the study design is not listed, you may add the appropriate study design.
4. Mean age
Report across all patients included in relevant study arms. Round to whole number. Include the word "years" after reporting the mean age.
5. % male
Report across all patients included in relevant study arms. Round to whole number. Include "%" symbol.
6. % Non-white
Report across all patients included in relevant study arms. Round to whole number. Include "%" symbol. If not reported, put NR.
7. Mean duration of pain or symptoms
Report across all patients included in relevant study arms. Round to whole number. Report duration in terms of months. If not reported, put NR.
8. Pain etiology/type
9. Disability
Disability can be measured in several ways. For example, authors may report the percent of patients receiving disability payments or they may report the mean score of a continuous disability scale such as the Pain Disability Index. Either are appropriate here, just be explicit about what is being reported.
10. Comorbidities
Extract the percent of patients with relevant comorbidities. Round percentages to whole numbers. If not reported, put NR.
% Depression diagnosis
% Anxiety diagnosis
% PTSD disagnosis
% Overweight or obese
% w/ Substance Use Disorder
% Smokers
% Suicidal
11. Randomized, Analyzed, and Attrition (at longest followup point)
For attrition report as: % (n/N)
Randomized
Analyzed
Attrition
12. How was the study funded?
13. Notes and comments

Arms

Arm NameArm Description
IPMP
Usual careAll clinicians have access to the medical center's specialty pain clinic, onsite mental health services, and ancillary services including physical, occupational, and recreational therapy

Arm Details

1. Is the program practice-based or system-based?
IPMP
Usual care
2. How many patients were randomized to this treatment arm?
IPMP
Usual care
3. Program duration (weeks)
Please report the duration of the program in weeks and include "weeks" in the text box.
IPMP
Usual care
4. Number of sessions per week
Report as X sessions/week
IPMP
Usual care
5. Was the program conducted in the inpatient or outpatient setting?
Select one.
IPMP
Usual care
6. Physical Functioning/Reconditioning & Psychological and Mental Health Components of Intervention
For treatment providers, you may write-in any options that are needed that are not already presented. For duration of treatment report as "X sessions per week over X weeks", when possible. For anything not reported, put NR.
IPMP
Physical Functioning/Reconditioning Components of InterventionPsychological and Mental Health Components of Intervention
Treatment types
Treatment providers
Mode of delivery
Duration of treatment
Tailoring
Adherence
Usual care
Physical Functioning/Reconditioning Components of InterventionPsychological and Mental Health Components of Intervention
Treatment types
Treatment providers
Mode of delivery
Duration of treatment
Tailoring
Adherence
7. Medication Review and/or Management Components of Intervention
IPMP
Usual care
8. Additional components of the intervention
IPMP
Usual care
9. Description of care coordination/collaboration
IPMP
Usual care

Sample Characteristics

N/A

Outcomes

TypeDomainSpecific measurement (i.e., tool/definition/specific outcome)PopulationsTimepoints
ContinuousFunctionRoland–Morris Disability Questionnaire
  • All Participants
  • Baseline
  • 3 months
  • 6 months
  • 12 months
  • 12 month ∆ from baseline
ContinuousPainChronic Pain Grade Severity/Intensity subscale
  • All Participants
  • Baseline
  • 3 months
  • 6 months
  • 12 months
  • 12 month ∆ from baseline
ContinuousFunctionChronic Pain Grade Disability/Interference subscale
  • All Participants
  • Baseline
  • 3 months
  • 6 months
  • 12 months
  • 12 month ∆ from baseline
ContinuousFunctionPain disability-free days
  • All Participants
  • 3 month ∆ from baseline
  • 12 month ∆ from baseline
CategoricalFunctionProportion of patients demonstrating a ≥30% reduction in RMDQ score
  • All Participants
  • 12 months
ContinuousQOLEQ-5D
  • All Participants
  • Baseline
  • 3 months
  • 6 months
  • 12 months
  • 12 month ∆ from baseline
ContinuousDepressionPHQ-9
  • All Participants
  • Baseline
  • 3 months
  • 6 months
  • 12 months
  • 12 month ∆ from baseline
ContinuousPatient satisfactionGlobal treatment satisfaction
  • All Participants
  • Baseline
  • 6 months
  • 12 months
  • 12 month ∆ from baseline
ContinuousPatient satisfactionGlobal impression of change in past 6 months
  • All Participants
  • 6 months
  • 12 months
ContinuousHealthcare utilizationNumber of primary care appointments during 52 week study period
  • All Participants
  • Immediately Post-intervention
ContinuousHealthcare utilizationNumber of ambulatory visits during 52 week study period
  • All Participants
  • Immediately Post-intervention
CategoricalHealthcare utilizationProportion of patients with any physical therapy appointment during 52 week study period
  • All Participants
  • Immediately Post-intervention
CategoricalHealthcare utilizationProportion of patients with any mental health appointment during 52 week study period
  • All Participants
  • Immediately Post-intervention
CategoricalHealthcare utilizationProportion of patients with any substance use disorder appointments during 52 week study period
  • All Participants
  • Immediately Post-intervention
CategoricalHealthcare utilizationProportion of patients with any pain specialty consultation service appointment during 52 week study period
  • All Participants
  • Immediately Post-intervention
CategoricalHealthcare utilizationProportion of patients with any emergency department visit during 52 week study period
  • All Participants
  • Immediately Post-intervention
CategoricalHealthcare utilizationProportion of patients with any inpatient admission during 52 week study period
  • All Participants
  • Immediately Post-intervention
CategoricalMedication useProportion of patients prescribed any opioid during 52 week study period
  • All Participants
  • Immediately Post-intervention
CategoricalMedication useProportion of patients prescribed any antidepressant during 52 week study period
  • All Participants
  • Immediately Post-intervention
CategoricalMedication useProportion of patients prescribed any NSAID during 52 week study period
  • All Participants
  • Immediately Post-intervention
CategoricalMedication useProportion of patients prescribed any Capsaicin during 52 week study period
  • All Participants
  • Immediately Post-intervention

Outcome Details

N/A

Risk of Bias Assessment

1. Randomization adequate?
Rating
2. Allocation concealment adequate?
Rating
3. Groups similar at baseline?
Rating
4. Outcome assessors masked?
Rating
5. Care providers masked?
Rating
6. Patient masked?
Rating
7. Reporting of attrition, crossovers, adherence, and contamination?
Rating
8. Loss to followup acceptable?
Overall ≤20%?
Difference between groups <10%?
9. Intention-to-treat (ITT) analysis?
Overall ≤20%?
10. Outcomes prespecified?
Overall ≤20%?
11. Quality determination
Overall ≤20%?

Results

Categorical


Function (Proportion of patients demonstrating a ≥30% reduction in RMDQ score)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
12 months
Total (N analyzed)
Odds Ratio (OR)
Events
95% CI low (OR)
Percentage
95% CI high (OR)
Proportion
p value
Mean
SD
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Healthcare utilization (Proportion of patients with any physical therapy appointment during 52 week study period)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Immediately Post-intervention
Total (N analyzed)
Mean Difference (MD)
Events
95% CI low (MD)
Percentage
95% CI high (MD)
Proportion
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Healthcare utilization (Proportion of patients with any mental health appointment during 52 week study period)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Immediately Post-intervention
Total (N analyzed)
Mean Difference (MD)
Events
95% CI low (MD)
Percentage
95% CI high (MD)
Proportion
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Healthcare utilization (Proportion of patients with any substance use disorder appointments during 52 week study period)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Immediately Post-intervention
Total (N analyzed)
Mean Difference (MD)
Events
95% CI low (MD)
Percentage
95% CI high (MD)
Proportion
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Healthcare utilization (Proportion of patients with any pain specialty consultation service appointment during 52 week study period)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Immediately Post-intervention
Total (N analyzed)
Mean Difference (MD)
Events
95% CI low (MD)
Percentage
95% CI high (MD)
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Healthcare utilization (Proportion of patients with any emergency department visit during 52 week study period)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Immediately Post-intervention
Total (N analyzed)
Odds Ratio (OR)
Events
95% CI low (OR)
Percentage
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Healthcare utilization (Proportion of patients with any inpatient admission during 52 week study period)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Immediately Post-intervention
Total (N analyzed)
Odds Ratio (OR)
Events
95% CI low (OR)
Percentage
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Medication use (Proportion of patients prescribed any opioid during 52 week study period)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Immediately Post-intervention
Total (N analyzed)
Mean Difference (MD)
Events
95% CI low (MD)
Percentage
95% CI high (MD)
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Medication use (Proportion of patients prescribed any antidepressant during 52 week study period)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Immediately Post-intervention
Total (N analyzed)
Mean Difference (MD)
Events
95% CI low (MD)
Percentage
95% CI high (MD)
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Medication use (Proportion of patients prescribed any NSAID during 52 week study period)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Immediately Post-intervention
Total (N analyzed)
Mean Difference (MD)
Events
95% CI low (MD)
Percentage
95% CI high (MD)
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Medication use (Proportion of patients prescribed any Capsaicin during 52 week study period)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Immediately Post-intervention
Total (N analyzed)
Mean Difference (MD)
Events
95% CI low (MD)
Percentage
95% CI high (MD)
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Continuous


Function (Roland–Morris Disability Questionnaire)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Baseline
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
3 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
6 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
12 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
12 month ∆ from baseline
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Pain (Chronic Pain Grade Severity/Intensity subscale)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Baseline
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
3 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
6 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
12 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
12 month ∆ from baseline
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Function (Chronic Pain Grade Disability/Interference subscale)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Baseline
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
3 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
6 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
12 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
12 month ∆ from baseline
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Function (Pain disability-free days)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
3 month ∆ from baseline
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
12 month ∆ from baseline
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
95% CI low
SD (MD)
95% CI high
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

QOL (EQ-5D)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Baseline
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
3 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
6 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
12 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
12 month ∆ from baseline
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Depression (PHQ-9)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Baseline
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
3 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
6 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
12 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
12 month ∆ from baseline
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Patient satisfaction (Global treatment satisfaction)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Baseline
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
6 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
12 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
12 month ∆ from baseline
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Patient satisfaction (Global impression of change in past 6 months)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
6 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
12 months
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
95% CI low
95% CI high (MD)
95% CI high
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Healthcare utilization (Number of primary care appointments during 52 week study period)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Immediately Post-intervention
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care

Healthcare utilization (Number of ambulatory visits during 52 week study period)

All Participants
Descriptive StatisticsBetween Arm Comparisons
IPMPUsual care
Immediately Post-intervention
Total (N analyzed)
Mean Difference (MD)
Mean
95% CI low (MD)
SD
95% CI high (MD)
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
IPMPUsual care