Extraction form for project: Interventional Treatments for Acute and Chronic Pain: Systematic Review
Design Details
1. Trial Intervention
Input which intervention is being studied
2. Trial Name
3. Setting
Country
4. Study Design
5. Mean Age (Years)
Input the mean age for the entire sample
6. Percent Female
Input the whole number here for the entire study sample - no need to add %
7. Number Randomized
8. Pain Duration Measure (Mean, Median)
9. Pain Duration (Weeks)
10. Duration of Followup (Months)
Arms
| Arm Name | Arm Description |
|---|---|
| Botulinum toxin type A piriformis injection | 100 units intramuscular injection under fluoroscopic guidance to piriformis muscle; placement verified with electromyography and pattern of radiotracer spread |
| Placebo injection | Intramuscular preservative-free normal saline injection as above |
Arm Details
N/A
Sample Characteristics
N/A
Outcomes
- All Participants
- 1 (week)
- 4 (weeks)
- 9 (weeks)
- All Participants
- 1 (week)
- 4 (weeks)
- 9 (weeks)
| Type | Domain | Specific measurement (i.e., tool/definition/specific outcome) | Populations | Timepoints |
|---|---|---|---|---|
| Continuous | Pain | Mean difference (95% CI), VAS 0 to 10 | ||
| Continuous | Function | Mean difference (95% CI) in interference with activities, VAS 0 to 10 |
Outcome Details
N/A
Risk of Bias Assessment
1. What kind of study is this?
2. Randomization adequate?
3. Allocation concealment adequate?
4. Groups similar at baseline?
5. Outcome assessors masked?
6. Care provider masked?
7. Patient masked?
8. Acceptable levels of overall attrition and between-group differences in attrition?
9. Intention-to-Treat (ITT) analysis?
10. Avoidance of selective outcomes reporting
11. Quality rating
Results
Continuous
Pain (Mean difference (95% CI), VAS 0 to 10)
| Descriptive Statistics | Between Arm Comparisons | ||||
|---|---|---|---|---|---|
| Botulinum toxin type A piriformis injection | Placebo injection | ||||
1 (week) | |||||
| mean difference | Mean Difference (MD) | ||||
| 95% CI low | 95% CI low (MD) | ||||
| 95% CI high | 95% CI high (MD) | ||||
| SD (MD) | |||||
| p value (MD) | |||||
4 (weeks) | |||||
| mean difference | Mean Difference (MD) | ||||
| 95% CI low | 95% CI low (MD) | ||||
| 95% CI high | 95% CI high (MD) | ||||
| SD (MD) | |||||
| p value (MD) | |||||
9 (weeks) | |||||
| mean difference | Mean Difference (MD) | ||||
| 95% CI low | 95% CI low (MD) | ||||
| 95% CI high | 95% CI high (MD) | ||||
| SD (MD) | |||||
| p value (MD) | |||||
| Within Arm Comparisons | Net Comparisons | ||||
| Botulinum toxin type A piriformis injection | Placebo injection | ||||
Function (Mean difference (95% CI) in interference with activities, VAS 0 to 10)
| Descriptive Statistics | Between Arm Comparisons | ||||
|---|---|---|---|---|---|
| Botulinum toxin type A piriformis injection | Placebo injection | ||||
1 (week) | |||||
| mean difference | Mean Difference (MD) | ||||
| 95% CI low | 95% CI low (MD) | ||||
| 95% CI high | 95% CI high (MD) | ||||
| SD (MD) | |||||
| p value (MD) | |||||
4 (weeks) | |||||
| mean difference | Mean Difference (MD) | ||||
| 95% CI low | 95% CI low (MD) | ||||
| 95% CI high | 95% CI high (MD) | ||||
| SD (MD) | |||||
| p value (MD) | |||||
9 (weeks) | |||||
| mean difference | Mean Difference (MD) | ||||
| 95% CI low | 95% CI low (MD) | ||||
| 95% CI high | 95% CI high (MD) | ||||
| SD (MD) | |||||
| p value (MD) | |||||
| Within Arm Comparisons | Net Comparisons | ||||
| Botulinum toxin type A piriformis injection | Placebo injection | ||||