Extraction form for project: Interventional Treatments for Acute and Chronic Pain: Systematic Review

Design Details

1. Trial Intervention
Input which intervention is being studied
2. Trial Name
3. Setting
Country
4. Study Design
5. Mean Age (Years)
Input the mean age for the entire sample
6. Percent Female
Input the whole number here for the entire study sample - no need to add %
7. Number Randomized
8. Pain Duration Measure (Mean, Median)
9. Pain Duration (Weeks)
10. Duration of Followup (Months)

Arms

Arm NameArm Description
Botulinum toxin type A piriformis injection200 units 2 ml intramuscular injection under electromyographic guidance (based on location of points at which 2 to 6 mA at 0.05 ms stimulus duration stimulated significant motility along the course of the piriformis muscle)
Corticosteroid piriformis injectionTriamcinolone acetonide: 20 mg in 0.5 ml solution + 1.5 ml of 2% lidocaine (2 ml total injection volume) intramuscular injection, as above
Placebo injection2 ml saline intramuscular injection as above

Arm Details

N/A

Sample Characteristics

N/A

Outcomes

TypeDomainSpecific measurement (i.e., tool/definition/specific outcome)PopulationsTimepoints
ContinuousPainRR (95% CI) of ≥50% improvement
  • All Participants
  • 3 (months)

Outcome Details

N/A

Risk of Bias Assessment

1. What kind of study is this?
2. Randomization adequate?
3. Allocation concealment adequate?
4. Groups similar at baseline?
5. Outcome assessors masked?
6. Care provider masked?
7. Patient masked?
8. Acceptable levels of overall attrition and between-group differences in attrition?
9. Intention-to-Treat (ITT) analysis?
10. Avoidance of selective outcomes reporting
11. Quality rating

Results

Continuous


Pain (RR (95% CI) of ≥50% improvement)

All Participants
Descriptive StatisticsBetween Arm Comparisons
Botulinum toxin type A piriformis injectionCorticosteroid piriformis injectionPlacebo injection
3 (months)
RR for A vs. C
Mean Difference (MD)
95% CI low
95% CI low (MD)
95% CI high
95% CI high (MD)
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
Botulinum toxin type A piriformis injectionCorticosteroid piriformis injectionPlacebo injection