Extraction form for project: Interventional Treatments for Acute and Chronic Pain: Systematic Review

Design Details

1. Trial Intervention
Input which intervention is being studied
2. Trial Name
3. Setting
Country
4. Study Design
5. Mean Age (Years)
Input the mean age for the entire sample
6. Percent Female
Input the whole number here for the entire study sample - no need to add %
7. Number Randomized
8. Pain Duration Measure (Mean, Median)
9. Pain Duration (Weeks)
10. Duration of Followup (Months)

Arms

Arm NameArm Description
Botulinum toxin type A piriformis injection300 units 3 ml intramuscular injection to 4 piriformis muscle sites (the most medial injection was made just lateral to the greater sciatic foramen along the line linking its midpoint to the greater trochanter) including the myoneural junctions of the S1 to S2 nerve fibers that innervate the piriformis muscle; placement with electromyographic guidance
Placebo injection3 ml saline injection as above

Arm Details

N/A

Sample Characteristics

N/A

Outcomes

TypeDomainSpecific measurement (i.e., tool/definition/specific outcome)PopulationsTimepoints
ContinuousPainMean (SD) change from baseline, scale unclear
  • All Participants
  • 4 (weeks)
  • 12 (weeks)

Outcome Details

N/A

Risk of Bias Assessment

1. What kind of study is this?
2. Randomization adequate?
3. Allocation concealment adequate?
4. Groups similar at baseline?
5. Outcome assessors masked?
6. Care provider masked?
7. Patient masked?
8. Acceptable levels of overall attrition and between-group differences in attrition?
9. Intention-to-Treat (ITT) analysis?
10. Avoidance of selective outcomes reporting
11. Quality rating

Results

Continuous


Pain (Mean (SD) change from baseline, scale unclear)

All Participants
Descriptive StatisticsBetween Arm Comparisons
Botulinum toxin type A piriformis injectionPlacebo injection
4 (weeks)
Mean
Mean Difference (MD)
SD
95% CI low (MD)
95% CI high (MD)
SD (MD)
p value (MD)
12 (weeks)
Mean
Mean Difference (MD)
SD
95% CI low (MD)
95% CI high (MD)
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
Botulinum toxin type A piriformis injectionPlacebo injection