Extraction form for project: Interventional Treatments for Acute and Chronic Pain: Systematic Review

Design Details

1. Trial Intervention
Input which intervention is being studied
2. Trial Name
3. Setting
Country
4. Study Design
5. Mean Age (Years)
Input the mean age for the entire sample
6. Percent Female
Input the whole number here for the entire study sample - no need to add %
7. Number Randomized
8. Pain Duration Measure (Mean, Median)
9. Pain Duration (Weeks)
10. Duration of Followup (Months)

Arms

Arm NameArm Description
Oxygen-ozone, corticosteroid, and local anesthetic injectionUnder CT guidance via paravertebral (92.4%) or interlaminar (7.6%) approach, intradiscal injection of 5 to 7 ml O2 to O3 (ozone concentration 28 μg/ml), 2 ml triamcinolone acetonide (1 ml in epidural space and 1 ml intradiscal) and 2 to 4 ml 2% ropivacaine (~2 ml in epidural space and 1 ml intradiscal); mean total volume 6.8 ml intradiscal and 9.5 ml intraforaminal (12.3 ml oxygen-ozone)
Corticosteroid and local anesthetic injectionCorticosteroid and local anesthetic as above, without oxygen-ozone; mean total volume 3 ml intradiscal and 2 ml intraforaminal

Arm Details

N/A

Sample Characteristics

N/A

Outcomes

TypeDomainSpecific measurement (i.e., tool/definition/specific outcome)PopulationsTimepoints
CategoricalFunctionODI <20%
  • All Participants
  • 2 (weeks)
  • 3 (months)
  • 6 (months)

Outcome Details

N/A

Risk of Bias Assessment

1. What kind of study is this?
2. Randomization adequate?
3. Allocation concealment adequate?
4. Groups similar at baseline?
5. Outcome assessors masked?
6. Care provider masked?
7. Patient masked?
8. Acceptable levels of overall attrition and between-group differences in attrition?
9. Intention-to-Treat (ITT) analysis?
10. Avoidance of selective outcomes reporting
11. Quality rating

Results

Categorical


Function (ODI <20%)

All Participants
Descriptive StatisticsBetween Arm Comparisons
Oxygen-ozone, corticosteroid, and local anesthetic injectionCorticosteroid and local anesthetic injection
2 (weeks)
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
95% CI high (OR)
p value
3 (months)
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
95% CI high (OR)
p value
6 (months)
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
Oxygen-ozone, corticosteroid, and local anesthetic injectionCorticosteroid and local anesthetic injection