Extraction form for project: Interventional Treatments for Acute and Chronic Pain: Systematic Review

Design Details

1. Trial Intervention
Input which intervention is being studied
2. Trial Name
3. Setting
Country
4. Study Design
5. Mean Age (Years)
Input the mean age for the entire sample
6. Percent Female
Input the whole number here for the entire study sample - no need to add %
7. Number Randomized
8. Pain Duration Measure (Mean, Median)
9. Pain Duration (Weeks)
10. Duration of Followup (Months)

Arms

Arm NameArm Description
Platelet-rich plasma injection1 to 2 ml of platelet-rich plasma injected mid-portion of discs that elicited concordant pain on discography with fluoroscopic guidance (for multiple discs, a total of 3 to 4 ml was split among the discs)
Sham1 to 2 ml contrast agent, as above

Arm Details

N/A

Sample Characteristics

N/A

Outcomes

TypeDomainSpecific measurement (i.e., tool/definition/specific outcome)PopulationsTimepoints
ContinuousPainNRS 0 to 10 worst pain, mean difference (95% CI)
  • All Participants
  • 1 (week)
  • 1 (month)
  • 2 (months)
ContinuousPainFRI 0 to 100, mean difference (95% CI)
  • All Participants
  • 1 (week)
  • 1 (month)
  • 2 (months)

Outcome Details

N/A

Risk of Bias Assessment

1. What kind of study is this?
2. Randomization adequate?
3. Allocation concealment adequate?
4. Groups similar at baseline?
5. Outcome assessors masked?
6. Care provider masked?
7. Patient masked?
8. Acceptable levels of overall attrition and between-group differences in attrition?
9. Intention-to-Treat (ITT) analysis?
10. Avoidance of selective outcomes reporting
11. Quality rating

Results

Continuous


Pain (NRS 0 to 10 worst pain, mean difference (95% CI))

All Participants
Descriptive StatisticsBetween Arm Comparisons
Platelet-rich plasma injectionSham
1 (week)
Mean difference
Mean Difference (MD)
95% CI low
95% CI low (MD)
95% CI high
95% CI high (MD)
SD (MD)
p value (MD)
1 (month)
Mean difference
Mean Difference (MD)
95% CI low
95% CI low (MD)
95% CI high
95% CI high (MD)
SD (MD)
p value (MD)
2 (months)
Mean difference
Mean Difference (MD)
95% CI low
95% CI low (MD)
95% CI high
95% CI high (MD)
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
Platelet-rich plasma injectionSham

Pain (FRI 0 to 100, mean difference (95% CI))

All Participants
Descriptive StatisticsBetween Arm Comparisons
Platelet-rich plasma injectionSham
1 (week)
Mean difference
Mean Difference (MD)
95% CI low
95% CI low (MD)
95% CI high
95% CI high (MD)
SD (MD)
p value (MD)
1 (month)
Mean difference
Mean Difference (MD)
95% CI low
95% CI low (MD)
95% CI high
95% CI high (MD)
SD (MD)
p value (MD)
2 (months)
Mean difference
Mean Difference (MD)
95% CI low
95% CI low (MD)
95% CI high
95% CI high (MD)
SD (MD)
p value (MD)
Within Arm ComparisonsNet Comparisons
Platelet-rich plasma injectionSham