Extraction form for project: Interventional Treatments for Acute and Chronic Pain: Systematic Review
Design Details
1. Trial Intervention
Input which intervention is being studied
2. Trial Name
3. Setting
Country
4. Study Design
5. Mean Age (Years)
Input the mean age for the entire sample
6. Percent Female
Input the whole number here for the entire study sample - no need to add %
7. Number Randomized
8. Pain Duration Measure (Mean, Median)
9. Pain Duration (Weeks)
10. Duration of Followup (Months)
Arms
| Arm Name | Arm Description |
|---|---|
| Platelet-rich plasma injection | 1 to 2 ml of platelet-rich plasma injected mid-portion of discs that elicited concordant pain on discography with fluoroscopic guidance (for multiple discs, a total of 3 to 4 ml was split among the discs) |
| Sham | 1 to 2 ml contrast agent, as above |
Arm Details
N/A
Sample Characteristics
N/A
Outcomes
- All Participants
- 1 (week)
- 1 (month)
- 2 (months)
- All Participants
- 1 (week)
- 1 (month)
- 2 (months)
| Type | Domain | Specific measurement (i.e., tool/definition/specific outcome) | Populations | Timepoints |
|---|---|---|---|---|
| Continuous | Pain | NRS 0 to 10 worst pain, mean difference (95% CI) | ||
| Continuous | Pain | FRI 0 to 100, mean difference (95% CI) |
Outcome Details
N/A
Risk of Bias Assessment
1. What kind of study is this?
2. Randomization adequate?
3. Allocation concealment adequate?
4. Groups similar at baseline?
5. Outcome assessors masked?
6. Care provider masked?
7. Patient masked?
8. Acceptable levels of overall attrition and between-group differences in attrition?
9. Intention-to-Treat (ITT) analysis?
10. Avoidance of selective outcomes reporting
11. Quality rating
Results
Continuous
Pain (NRS 0 to 10 worst pain, mean difference (95% CI))
| Descriptive Statistics | Between Arm Comparisons | ||||
|---|---|---|---|---|---|
| Platelet-rich plasma injection | Sham | ||||
1 (week) | |||||
| Mean difference | Mean Difference (MD) | ||||
| 95% CI low | 95% CI low (MD) | ||||
| 95% CI high | 95% CI high (MD) | ||||
| SD (MD) | |||||
| p value (MD) | |||||
1 (month) | |||||
| Mean difference | Mean Difference (MD) | ||||
| 95% CI low | 95% CI low (MD) | ||||
| 95% CI high | 95% CI high (MD) | ||||
| SD (MD) | |||||
| p value (MD) | |||||
2 (months) | |||||
| Mean difference | Mean Difference (MD) | ||||
| 95% CI low | 95% CI low (MD) | ||||
| 95% CI high | 95% CI high (MD) | ||||
| SD (MD) | |||||
| p value (MD) | |||||
| Within Arm Comparisons | Net Comparisons | ||||
| Platelet-rich plasma injection | Sham | ||||
Pain (FRI 0 to 100, mean difference (95% CI))
| Descriptive Statistics | Between Arm Comparisons | ||||
|---|---|---|---|---|---|
| Platelet-rich plasma injection | Sham | ||||
1 (week) | |||||
| Mean difference | Mean Difference (MD) | ||||
| 95% CI low | 95% CI low (MD) | ||||
| 95% CI high | 95% CI high (MD) | ||||
| SD (MD) | |||||
| p value (MD) | |||||
1 (month) | |||||
| Mean difference | Mean Difference (MD) | ||||
| 95% CI low | 95% CI low (MD) | ||||
| 95% CI high | 95% CI high (MD) | ||||
| SD (MD) | |||||
| p value (MD) | |||||
2 (months) | |||||
| Mean difference | Mean Difference (MD) | ||||
| 95% CI low | 95% CI low (MD) | ||||
| 95% CI high | 95% CI high (MD) | ||||
| SD (MD) | |||||
| p value (MD) | |||||
| Within Arm Comparisons | Net Comparisons | ||||
| Platelet-rich plasma injection | Sham | ||||