Design Details
Arms
Arm Details
Sample Characteristics
Outcomes
Outcome Details
Risk of Bias Assessment
Results
Print Data

Extraction form for project: Acute Pain Updates

Design Details

1. Setting

Column B

2. Country

Column C

3. Specific Pain Condition

Column D

4. Intervention Types Compared

Column E

5. Number randomized


Total	129
Intervention A	Not reported
Intervention B	Not reported

6. Number Analyzed


Total	107
Intervention A	45
Intervention B	62

7. Participants age (mean, years)


	47.8

8. Participants sex (% Female)


	49

9. Race (%)

Column L


	Not reported

10. History of Substance Use Disorder

Column N

11. Under Treatment for Opiate Use Disorder

Column O

12. History of Psychiatric Illness

Column P

13. Pregnant or Breastfeeding

Column R

14. Pain Duration

Column R


	Postoperative

15. Overall Baseline Pain Standardized Scale 0 to 10

Column S


	3.56 (Not reported)

16. Treatment duration

Column T


	14 days

17. Assessment Time Points

Column V

18. Duration of Followup Category

Column W

Arms

Arm Name	Arm Description
Intervention A	Preoperative opioid education
Intervention B	No preoperative opioid education

Arm Details

N/A

Sample Characteristics

N/A

Outcomes

Type	Domain	Specific measurement (i.e., tool/definition/specific outcome)	Populations	Timepoints
Continuous	Pain	Pain intensity (mean [SD NR], 0 to 10 VAS)	All Participants	Day 3 after treatment Day 4 after treatment Day 5 after treatment
Continuous	Persistent Opioid Use and Prescribing Rates	Opioid consumption, day 0 to 14 (mg morphine equivalents [SD]	All Participants	Day 0 to 14 after treatment

Outcome Details

N/A

Risk of Bias Assessment

1. Was randomization adequate?

2. Was allocation concealment adequate?

3. Were the groups similar at baseline?

4. Were the outcome assessor masked?

5. Were the care providers masked?

6. Was the patient masked?

7. Did the article report attrition, crossovers, adherence and/or contamination?

8. Loss to followup?


Differential
High

9. Was there intention-to-treat analysis?

10. Were there post-randomization exclusions?

11. Were the outcomes prespecified?

12. Quality rating

Results

Continuous

Pain (Pain intensity (mean [SD NR], 0 to 10 VAS))

All Participants
		Descriptive Statistics			Between Arm Comparisons
		Intervention A	Intervention B
Day 3 after treatment
	Mean			Mean Difference (MD)
	SD			95% CI low (MD)
				95% CI high (MD)
				SD (MD)
				p value (MD)
Day 4 after treatment
	Mean			Mean Difference (MD)
	SD			95% CI low (MD)
				95% CI high (MD)
				SD (MD)
				p value (MD)
Day 5 after treatment
	Mean			Mean Difference (MD)
	SD			95% CI low (MD)
				95% CI high (MD)
				SD (MD)
				p value (MD)
		Within Arm Comparisons			Net Comparisons
		Intervention A	Intervention B

Persistent Opioid Use and Prescribing Rates (Opioid consumption, day 0 to 14 (mg morphine equivalents [SD])

All Participants
		Descriptive Statistics			Between Arm Comparisons
		Intervention A	Intervention B
Day 0 to 14 after treatment
	Mean			Mean Difference (MD)
	SD			95% CI low (MD)
				95% CI high (MD)
				SD (MD)
				p value (MD)
		Within Arm Comparisons			Net Comparisons
		Intervention A	Intervention B