Extraction form for project: Screening for Glaucoma in Adults - 1 of 2

Design Details

1. Study design

Arms

Arm NameArm Description
Timolol 0.5% twice daily (n=35)
No treatment (n=35)Fellow eyes of same individuals

Sample Characteristics

1. N
Timolol 0.5% twice daily (n=35)
No treatment (n=35)
Total
2. Baseline population
Timolol 0.5% twice daily (n=35)
No treatment (n=35)
Total

Outcomes

TypeDomainSpecific measurement (i.e., tool/definition/specific outcome)PopulationsTimepoints
CategoricalVision disorderIntraocular pressure 48 months
  • All Participants
  • 48 months

Risk of Bias Assessment

1. Random assignment
2. Allocation concealed
3. Groups similar at baseline
4. Eligibility criteria specified
5. Blinding: outcome assessors or data analysts
6. Intention-to-treat analysis
7. Reporting of attrition, contamination, etc.
8. Differential loss to followup or overall high loss to followup
9. Appropriate analysis including cluster correlation
10. Funding source
11. Randomization adequate?
12. Allocation concealment adequate?
13. Groups similar at baseline?
14. Eligibility criteria specified?
15. Outcome assessors masked?
16. Care provider masked?
17. Patient masked?
18. Attrition and withdrawals reported?
19. Loss to followup differential/ high?
20. People analyzed in the groups in which they were randomized?
21. Quality

Results

Categorical


Vision disorder (Intraocular pressure 48 months)

All Participants
Descriptive StatisticsBetween Arm Comparisons
Timolol 0.5% twice daily (n=35)No treatment (n=35)
48 months
intraocular pressure (IOP)
Odds Ratio (OR)
Mean difference
95% CI low (OR)
p-value
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
Timolol 0.5% twice daily (n=35)No treatment (n=35)