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Arm Name | Arm Description |
---|---|

A. Latanaprostene bunod 0.024% four times per day (n=562) | |

B. Timolol 0.5% twice per day (n=269) |

- All Participants
- end of study
- All Participants
- end of study
- All Participants
- end of study
- All Participants
- end of study

Type | Domain | Specific measurement (i.e., tool/definition/specific outcome) | Populations | Timepoints |
---|---|---|---|---|

Categorical | Vision disorder | Intraocular pressure (IOP) ≤18 mmHg at all timepoints | ||

Categorical | Vision disorder | Intraocular pressure (IOP) reduced ≥25% at all timepoints | ||

Continuous | Harm/adverse event | Serious adverse events | ||

Continuous | Harm/adverse event | Withdrawal due to adverse events |

Descriptive Statistics | Between Arm Comparisons | ||||
---|---|---|---|---|---|

A. Latanaprostene bunod 0.024% four times per day (n=562) | B. Timolol 0.5% twice per day (n=269) | vs. | |||

end of study | |||||

Percentage | p value | ||||

Within Arm Comparisons | Net Comparisons | ||||

A. Latanaprostene bunod 0.024% four times per day (n=562) | B. Timolol 0.5% twice per day (n=269) | vs. |

Descriptive Statistics | Between Arm Comparisons | ||||
---|---|---|---|---|---|

A. Latanaprostene bunod 0.024% four times per day (n=562) | B. Timolol 0.5% twice per day (n=269) | vs. | |||

end of study | |||||

Percentage | p value | ||||

Within Arm Comparisons | Net Comparisons | ||||

A. Latanaprostene bunod 0.024% four times per day (n=562) | B. Timolol 0.5% twice per day (n=269) | vs. |

Descriptive Statistics | Between Arm Comparisons | ||||
---|---|---|---|---|---|

A. Latanaprostene bunod 0.024% four times per day (n=562) | B. Timolol 0.5% twice per day (n=269) | ||||

end of study | |||||

Percentage | Relative risk (RR) (95% CI) | ||||

Mean Difference (MD) | |||||

95% CI low (MD) | |||||

95% CI high (MD) | |||||

SD (MD) | |||||

p value (MD) | |||||

Within Arm Comparisons | Net Comparisons | ||||

A. Latanaprostene bunod 0.024% four times per day (n=562) | B. Timolol 0.5% twice per day (n=269) |

Descriptive Statistics | Between Arm Comparisons | ||||
---|---|---|---|---|---|

A. Latanaprostene bunod 0.024% four times per day (n=562) | B. Timolol 0.5% twice per day (n=269) | vs. | |||

end of study | |||||

Percentage | Relative risk (RR) (95% CI) | ||||

Within Arm Comparisons | Net Comparisons | ||||

A. Latanaprostene bunod 0.024% four times per day (n=562) | B. Timolol 0.5% twice per day (n=269) | vs. |