Extraction form for project: ESP Troponin ADPs

Design Details

1. Cohort name
Cohort, not ADP, name
2. Protocol number (eg, NCT)
3. Copublications
List other records that were extracted with this primary articles. Eg, PMIDs or other identifiers
4. Study design
5. Study years
Just years. Not publication year. Years of study. You may need to estimate. Use tilde (~) if you're approximating. If not reported, put "< ####" (the publication or submission year).
StartEnd
6. Funding
Include provision of materials (eg, cTn labs) from industry as industry funding
7. Country/ies
NR should rarely if ever be selected
8. Setting
9. Centers
If Unclear, add a note why
10. Inclusion criteria
ACS row = Eligibility criteria specific to acute coronary syndrome symptoms/signs. Age/Gender = criteria specific to age/gender. Prior CVD = restriction based on prior cardiovascular disease, event, or procedure. Other = other inclusion criteria. Skip rows that do not pertain. Be concise.
ACS
Age
Gender
Prior CVD
Other
11. Exclusion criteria
Prior CVD = exclusion based on prior cardiovascular disease, event, or procedure. Other = other exclusion criteria. Skip rows that do not pertain. Be concise.
STEMI
Prior CVD
Comorbidity
Other
12. Special/Atypical population
Highlight if this is a specific group of patients. Skip if no particular relevant exclusion criteria
13. Comments/Notes

Arms

Arm NameArm Description
not hs-cTnPre-implementation Phase
hs-cTn ESC 0/1-h algorithm + clinical assessment (medical history, physical examination, standard blood test including serial measurements of (hs-cTnT), ECG)

Arm Details

1. hs-cTn info
Click NR checkboxes in each row with no reported data
not hs-cTn
DataNR
Test name
Manufacturer
Generation
Limit of detection (ng/L)
Comment/Note
99th %ile
hs-cTn
DataNR
Test name
Manufacturer
Generation
Limit of detection (ng/L)
Comment/Note
99th %ile

Sample Characteristics

1. N Enrolled
2. Age
3. % Male
4. Race/Ethnicity, %
White
White, Non-Hispanic
Black
Hispanic/Latino
Asian (any)
East Asian
South Asian
Other 1
Other 2
Other 3
NR
5. Are there significant differences (statistical or clinical) between the two groups?
6. History of Cardiovascular Disease, %
peripheral arterial disease
Stroke/TIA
Prior MI
prior revascularization (eg., CABG, PCI)
History of Cardiovascular Disease
7. Risk Factors for Cardiovascular Disease, %
Comments
Hypertension
Diabetes
Smoking Histrory
BMI/obesity
Family History
Hyperlipidemia
8. Risk Score
Enter risk score name (eg Heart), mean (SD) or thresholds and proportions
Name Risk ScoreThresholdProportion, %Mean (SD)Comment
Risk Score 1
Risk Score 2
Risk Score 3
Risk Score 4
9. Notes/Comments

Outcomes

TypeDomainSpecific measurement (i.e., tool/definition/specific outcome)PopulationsTimepoints
ContinuousED Visit durationTime spent on the ED, min
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • ED visit (min)
ContinuousHospitalization durationOvernight stays, nights
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • Hospitalization
CategoricalCardiac testingCardiac stress testing
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • 30 (d)
CategoricalCardiac testingCardiac stress testing (Functional imaging defined as stress echocardiography or myocardial perfusion scintigraphy)
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • 30 (d)
CategoricalCardiac testingCardiac stress testing (Ergometry)
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • 30 (d)
CategoricalCardiac testingCoronary angiography
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • 30 (d)
CategoricalCardiac testingNo CAD testing
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • 30 (d)
CategoricalCardiac testingNo further outpatient testing for CAD
  • Rule out and discharged directly from ED
  • 30 (d)
CategoricalCardiac revascularizationPCI
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • 30 (d)
CategoricalCardiac revascularizationRevascularization
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • 30 (d)
CategoricalCardiac revascularizationCABG
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • 30 (d)
CategoricalMACEMACE (The composite of death and MI)
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • 30 (d)
CategoricalMI, anyMI at index admission
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • 30 (d)
CategoricalMACEMACE during follow-up
  • All Participants
  • 30 (d)
CategoricalMACE MACE missed by ESC 0/1 algorithm
  • Rule out
  • 30 (d)
CategoricalMI, anyMyocardial infarction s during 30-day follow-up
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • 30 (d)
  • At index admission
  • During follow up
CategoricalMI, missed/delayedMissed by ESC 0/1 the algorithm
  • Rule out
  • 30 (d)
CategoricalDeath, all-causeDeath
  • All participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • 30 (d)
CategoricalDeath, cardiovascularCardiovascular death
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • Outpatient
  • Inpatient
  • 30 (d)
CategoricalImplementation / Adherence Without protocol violations
  • All Participants
  • ED visit
CategoricalImplementation/AdherenceThe most frequent protocol violation: ED discharge without collection of a second (1-h) hs-cTnT measurement. in patients presenting within the first 3 h after chest pain onset
  • All Participants
  • ED visit
CategoricalImplementation/AdherenceNo serial hs-cTnT testing after the initial measurement in patients presenting within the first 3 h after the chest pain onset treated as inpatients
  • All Participants
  • ED visit
CategoricalImplementation/AdherenceFirst hs-cTnT retesting was performed after 3 h instead of 1
  • All Participants
  • ED visit
CategoricalImplementation/AdherenceIn patients triaged toward rule-out by the algorithm: required additional cardiac investigations on the ED including hs-cTnT measurements at later time points (e.g., 3 to12 h) or coronary CT angiography
  • All Participants
  • ED visit
CategoricalImplementation/AdherenceSubsequent cardiac stress testing within 30 days and not during ED stay
  • Rule out
  • Outpatients
  • 30 (d)
CategoricalImplementation/AdherenceHospitalized in a monitored unit in rule in group
  • Rule in
  • ED visit
CategoricalImplementation/Adherenceunderwent early coronary angiography in rule in group
  • Rule in
  • ED visit
CategoricalImplementation / Adherence Performance: Proportion Outpatients
  • CPO ≤3 hours
  • CPO >3 hours
  • Sex: Females
  • Sex: Males
  • Age: >65 years
  • Age: ≤65 years
  • ED visit
CategoricalImplementation / Adherence ADHERENCE AND RESOURCE USE: admitted and left the hospital against the medical advice on the day of admission
  • All participants
  • Rule out
  • Rule in
  • ED visit
CategoricalHospitalizationDischarge directly from the ED
  • All participants
  • Rule out
  • Observe
  • Rule in
  • ED visit
CategoricalHospitalizationIncorrectly triaged toward treated as outpatient (inappropriate discharge rate)
  • MI at index admission
  • 30 (d)
CategoricalHospitalizationInpatient, admitted not discharged
  • All Participants
  • Rule out
  • Observe
  • Rule in
  • ED visit
CategoricalMI, missed/delayedDue to incorrectly triaged toward rule-out for NSTEMI (Missed MI rate)
  • MI at index admission
  • 30 (d)
CategoricalMACEMACE in subgroups
  • CPO ≤3 hours Rule-out group
  • CPO >3 hours Rule-out group
  • Sex: Females Rule-out group
  • Sex: Males Rule-out group
  • Age: >65 years Rule-out group
  • Age: ≤65 years Rule-out group
  • CPO ≤3 hours Outpatients group
  • CPO >3 hours Outpatients group
  • Sex: Females Outpatients group
  • Sex: Males Outpatients group
  • Age: >65 years Outpatients group
  • Age: ≤65 years Outpatients group
  • 30 (d)

Outcome Details

1. MI definition
Universal definitions refer to ESC/ACC/AHA/WHF (or Global MI) task forces. If an Other definition, provide details in 2nd row and the cited reference for their definition in the 3rd row.
ED Visit duration
Universal
Other
Other reference
Hospitalization duration
Universal
Other
Other reference
Cardiac testing
Universal
Other
Other reference
Cardiac testing
Universal
Other
Other reference
Cardiac testing
Universal
Other
Other reference
Cardiac testing
Universal
Other
Other reference
Cardiac testing
Universal
Other
Other reference
Cardiac testing
Universal
Other
Other reference
Cardiac revascularization
Universal
Other
Other reference
Cardiac revascularization
Universal
Other
Other reference
Cardiac revascularization
Universal
Other
Other reference
MACE
Universal
Other
Other reference
MI, any
Universal
Other
Other reference
MACE
Universal
Other
Other reference
MACE
Universal
Other
Other reference
MI, any
Universal
Other
Other reference
MI, missed/delayed
Universal
Other
Other reference
Death, all-cause
Universal
Other
Other reference
Death, cardiovascular
Universal
Other
Other reference
Implementation / Adherence
Universal
Other
Other reference
Implementation/Adherence
Universal
Other
Other reference
Implementation/Adherence
Universal
Other
Other reference
Implementation/Adherence
Universal
Other
Other reference
Implementation/Adherence
Universal
Other
Other reference
Implementation/Adherence
Universal
Other
Other reference
Implementation/Adherence
Universal
Other
Other reference
Implementation/Adherence
Universal
Other
Other reference
Implementation / Adherence
Universal
Other
Other reference
Implementation / Adherence
Universal
Other
Other reference
Hospitalization
Universal
Other
Other reference
Hospitalization
Universal
Other
Other reference
Hospitalization
Universal
Other
Other reference
MI, missed/delayed
Universal
Other
Other reference
MACE
Universal
Other
Other reference
2. MACE components
If a checked component has an asterisk (*), confirm with team before extracting the MACE outcome
ED Visit duration
Hospitalization duration
Cardiac testing
Cardiac testing
Cardiac testing
Cardiac testing
Cardiac testing
Cardiac testing
Cardiac revascularization
Cardiac revascularization
Cardiac revascularization
MACE
MI, any
MACE
MACE
MI, any
MI, missed/delayed
Death, all-cause
Death, cardiovascular
Implementation / Adherence
Implementation/Adherence
Implementation/Adherence
Implementation/Adherence
Implementation/Adherence
Implementation/Adherence
Implementation/Adherence
Implementation/Adherence
Implementation / Adherence
Implementation / Adherence
Hospitalization
Hospitalization
Hospitalization
MI, missed/delayed
MACE

Results

Categorical


Cardiac testing (Cardiac stress testing)

All Participants
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule out
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Observe
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule in
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Outpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Inpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn

Cardiac testing (Cardiac stress testing (Functional imaging defined as stress echocardiography or myocardial perfusion scintigraphy))

All Participants
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule out
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Observe
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule in
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Outpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Inpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn

Cardiac testing (Cardiac stress testing (Ergometry))

All Participants
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule out
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Observe
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule in
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Outpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Inpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn

Cardiac testing (Coronary angiography)

All Participants
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule out
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Observe
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule in
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Outpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Inpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn

Cardiac testing (No CAD testing)

All Participants
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule out
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Observe
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule in
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Outpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Inpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn

Cardiac testing (No further outpatient testing for CAD)

Rule out and discharged directly from ED
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
95%Cl Low
Comment
95% CI High
Odds Ratio (OR)
Total (N analyzed)
95% CI low (OR)
Events
95% CI high (OR)
Percentage
p value
Note
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn

Cardiac revascularization (PCI)

All Participants
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule out
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Observe
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule in
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Outpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Inpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn

Cardiac revascularization (Revascularization)

All Participants
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule out
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Observe
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule in
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Outpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Inpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn

Cardiac revascularization (CABG)

All Participants
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule out
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Observe
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule in
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Outpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Inpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn

MACE (MACE (The composite of death and MI))

All Participants
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
p value
Percentage
Note
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule out
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Observe
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule in
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Outpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
hs-cTn ( ESC 0/1-h...)
vs.
not hs-cTn (Pre-implement...)
30 (d)
95%Cl Low
Comment
95% CI High
p value
Total (N analyzed)
Events
Percentage
Note
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
hs-cTn ( ESC 0/1-h...)
vs.
not hs-cTn (Pre-implement...)
Inpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
Note
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn

MI, any (MI at index admission)

All Participants
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
p value
Percentage
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule out
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Observe
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Rule in
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
Outpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
not hs-cTn (Pre-implement...)
vs.
hs-cTn ( ESC 0/1-h...)
30 (d)
Total (N analyzed)
Comment
Events
p value
Percentage
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn
not hs-cTn (Pre-implement...)
vs.
hs-cTn ( ESC 0/1-h...)
Inpatient
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
30 (d)
Total (N analyzed)
Comment
Events
Odds Ratio (OR)
Percentage
95% CI low (OR)
95% CI high (OR)
p value
Within Arm ComparisonsNet Comparisons
not hs-cTnhs-cTn

MACE (MACE during follow-up)

All Participants
Descriptive StatisticsBetween Arm Comparisons
not hs-cTnhs-cTn
not hs-cTn (Pre-implement...)
vs.
hs-cTn ( ESC 0/1-h...)
30 (d)
Total (N analyzed)
Comment
Events
p value
Percentage
Note